Research

Learn about published research as well as leading-edge basic and translational research initiatives from St. Jude laboratories.

Researchers take the fight to drug resistance up an octave
Researchers take the fight to drug resistance up an octave

Researchers take the fight to drug resistance up an octave

Robert J. Autry and William E. Evans, PharmD

Drug resistance is a major reason for treatment failure in children with leukemia, but recent research may have an answer.

Learning more about T cells through studying behavior in Type 1 diabetes
Learning more about T cells through studying behavior in Type 1 diabetes

Learning more about T cells through studying behavior in Type 1 diabetes

Ben Youngblood, PhD

Learning more about how the body attacks itself in Type 1 diabetes offers insights into how to harness the power of T cells to treat cancer.

Discovery shows oxygen’s role in neuron development
Discovery shows oxygen’s role in neuron development

Discovery shows oxygen’s role in neuron development

David J. Solecki, PhD

Read how oxygen’s role neuron development is critical for brain health in infants.

Pushing the limits to find relationship between proteomics and Alzheimer’s
Pushing the limits to find relationship between proteomics and Alzheimer’s

Pushing the limits to find relationship between proteomics and Alzheimer’s

Mary Powers

Read how a 20-year wait for technology shows key insights in brain proteins’ role in the development and progression of Alzheimer’s.

Microscopes: Paths and barriers to discovery and super resolution
Microscopes: Paths and barriers to discovery and super resolution

Microscopes: Paths and barriers to discovery and super resolution

David J. Solecki, PhD

Combining microscopes allows for a resolution that allows scientists to see deep into a cell and how neurons organize gene expression in cell formation.

Importance of citations in scientific research: More than just bragging rights
Importance of citations in scientific research: More than just bragging rights

Importance of citations in scientific research: More than just bragging rights

Rebecca Tweedell, PhD

Being highly cited means your research gets published in high-impact journals and reaches more people.

Smithsonian honors St. Jude visionaries for ‘bubble boy’ cure
Smithsonian honors St. Jude visionaries for ‘bubble boy’ cure

Smithsonian honors St. Jude visionaries for ‘bubble boy’ cure

Mary Powers

Read how St. Jude researchers and clinicians used gene therapy to cure the diabolical bubble boy disease.

Proteins: Playing with molecular rubber duckies
Proteins: Playing with molecular rubber duckies

Proteins: Playing with molecular rubber duckies

Marcus Fischer, PhD

Are you a match? Read how this molecule’s affinity to proteins can change according to water.

New analytical technique reveals the subtle genetic differences among cancer cells
New analytical technique reveals the subtle genetic differences among cancer cells

New analytical technique reveals the subtle genetic differences among cancer cells

Xiang Chen, PhD

Sequencing data gives insights into what’s going on in a cell. It’s a lot of information. Read how scientists are finding ways to cut through the information and find causes for disease.

Genetic sequencing: How do we put out the fires of genetically driven cancers?
Genetic sequencing: How do we put out the fires of genetically driven cancers?

Genetic sequencing: How do we put out the fires of genetically driven cancers?

Jill Bouchard, PhD

Too much of a good thing? Read how genetic sequencing offers insights into the causes of some cancers, but the avalance of data creates a new set of issues.