Research

Learn about published research as well as leading-edge basic and translational research initiatives from St. Jude laboratories.

Paul Taylor, et al
Paul Taylor, et al

Preventing neurodevelopmental disorders through genetic compensation

Brian O'Flynn, PhD

See how a gene family is implicated in the cause and rescue of neurodegenerative disease

Nuclear receptor DNA
Nuclear receptor DNA

Electrical engineering sparks discovery in how human nuclear receptors bind to DNA

Brian O'Flynn, PhD

See how nuclear receptors selectively bind to DNA.

Shondra Pruett-Miller, PhD, and Jamaica Siwak at work
Shondra Pruett-Miller, PhD, and Jamaica Siwak at work

Shared Resources Spotlight: Center for Advanced Genome Engineering

Elizabeth Casolo

Research from the Center for Applied Genome Engineering plays a pivotal role in discovery.

Yurika Matsui, PhD, Jamy Peng, PhD, Beisi Xu, PhD,
Yurika Matsui, PhD, Jamy Peng, PhD, Beisi Xu, PhD,

The life and death of cells in early brain development

Brian O'Flynn, PhD

Explore St. Jude research on neural cell life or death during brain development.

Thalassemia illustration
Thalassemia illustration

Missed connection no more: Science and serendipity solve a microRNA mystery

Alex Generous, PhD

Find how a St. Jude discovery holds new promise for beta-thalassemia.

. L to R: Gang Wu, PhD, Wojciech Rosikiewicz, PhD, Wenjie Qi, PhD, Jason Myers, Beisi Xu, PhD.
. L to R: Gang Wu, PhD, Wojciech Rosikiewicz, PhD, Wenjie Qi, PhD, Jason Myers, Beisi Xu, PhD.

Shared Resources Spotlight: Center for Applied Bioinformatics

Elizabeth Casolo

Meet the data scientists advancing research at St. Jude.

Global TRM illustration
Global TRM illustration

Addressing treatment-related mortality: Student’s research spotlights need for supportive care

Erin Podolak, MA

Gathering data increases understanding of treatment-related mortality in low- and middle-income countries.

Vevea cover art
Vevea cover art

On the Road to Discovery: How Understanding Mitochondrial Trafficking Drives Change

Jessica Gullett-Rubino, PhD

Explore how mitochondrial research in the Vevea lab sheds light on neurons.

Nicholas Phillips
Nicholas Phillips

Healthy lifestyles: mitigating the risk of cognitive impairment in childhood cancer survivors

Alex Generous, PhD

Discover how healthy lifestyles may protect cognitive abilities in childhood cancer survivors.

Gabriela Maron, Ellie Margolis and Li Tang at an anerobic hood
Gabriela Maron, Ellie Margolis and Li Tang at an anerobic hood

Spilling their guts: patient microbiomes may hold the secret to predicting outcomes after transplant

Alex Generous, PhD

Gut microbiome predicts pediatric bone marrow transplant infections and other complications.