Research
Learn about published research as well as leading-edge basic and translational research initiatives from St. Jude laboratories.
Two Years of the Pediatric Translational Neuroscience Initiative
St. Jude initiative aims to change the outlook for children with catastrophic neurological diseases.
T cells are key to maintaining cancer remissions from chemotherapy
Stimulating the adaptive immune response can improve outcomes for ALL treated with chemotherapy.
St. Jude researchers answer COVID questions
St. Jude research has advanced understanding of the immune response to SARS-CoV-2 infection and vaccination. Here is what the findings mean for you.
Research points to a way to reduce cachexia, a cancer-induced muscle wasting disorder
Muscle signaling provide clues for treatment of the muscle-wasting disorder cachexia, which affects cancer patients.
Metabolic processes may yield a new therapeutic window for hard-to-treat brain tumors
In his laboratory at St. Jude, Stephen Mack, PhD, is researching how metabolic and epigenetic pathways might be perturbed to help treat DIPG, a lethal childhood brain tumor.
St. Jude symposium to focus on hippocampus imaging in childhood cancer patients and survivors
St. Jude Children’s Research Hospital’s Department of Diagnostic Imaging is hosting their 3rd Annual Scientific Symposium, “Imaging Structure and Functions of the Hippocampus” on February 25.
Pain may be a risk factor for learning problems in childhood cancer survivors
Researchers are focusing on treatment-related pain as another way to reduce the risk of learning and memory problems in survivors of childhood leukemia.
CoNGA: Deciphering the dance of T-cell differentiation
St. Jude scientists have created an algorithm to help group T-cells by their function by evaluating two different types of data, T-cell receptor sequences and gene expression.
St. Jude biostatisticians create a novel clinical trial design software
Description: St. Jude biostatisticians have developed a new method for designing phase 2 clinical trials with a small sample size. The approach uses a mathematical model called Bayesian probability . The researchers created free software to implement the process.
Bringing Chemistry to Medicine: Transcription therapy symposium is set for July 22 and 23
St. Jude will host the virtual Bringing Chemistry to Medicine Symposium July 22–23. The inaugural event in 2020 prompted a researcher in India to become a visiting scientist at St. Jude. Register for the event.