Research

Learn about published research as well as leading-edge basic and translational research initiatives from St. Jude laboratories.

Protein turnover information provides new insights and may guide researchers to more accurate Alzheimer's disease models

Brian O'Flynn, PhD

See how a collaborative effort in proteomics produced a comprehensive turnover atlas and sparked discovery in Alzheimer’s disease research.

Alejandro Gutierrez
Alejandro Gutierrez

Unassuming enzyme adds fuel to the fire in liposarcoma

Brian O'Flynn, PhD

Discover methyltransferase’s sarcoma side-gig

Group of people in a lab talking by a giant computer screen
Group of people in a lab talking by a giant computer screen

Quantum computing makes waves in drug discovery

Alex Generous, PhD

Learn how quantum computing is being used at St. Jude.

A curative gene therapy for Diamond-Blackfan anemia nears the clinic

Alex Generous, PhD

Find how St. Jude researchers are pushing forward a potential cure for DBA.

St. Jude scientists do more with less using PeCan-Seq liquid biopsy

Alex Generous, PhD

Novel plasma test shows promise.

Cre matters: Neuroblastoma oncogene activation controls what type of tumor forms

Brian O'Flynn, PhD

See how rare pancreatic cancer is triggered in neuroblastoma model

Working from the same playbook to characterize rare sarcoma

Brian O'Flynn, PhD

See how pooling rhabdomyosarcoma datasets uncovered new insights into the rare pediatric cancer

two men at a whiteboard
two men at a whiteboard

Shared Resources Spotlight: Cytogenetics

Emilia Asante, PhD

The St. Jude Cytogenetics Shared Resource uses advanced imaging techniques to visualize DNA, RNA, and protein interactions within cells.

Your fatty acid delivery is on the way: studying cellular logistics provides disease insights

Paige Brown Jarreau, PhD

A paper from the laboratory of Chi-Lun Chang, PhD, details their new toolkit, FABCON, for detecting contact sites where organelles exchange material.

dali-like illustration of clocks in a wasteland
dali-like illustration of clocks in a wasteland

The ticking ‘epigenetic’ clock measures true biological age

Alex Generous, PhD

Dive into research on the ‘epigenetic clock’ and learn how understanding it can help childhood cancer survivors.