St. Jude Research

Research

Learn about published research as well as leading-edge basic and translational research initiatives from St. Jude laboratories.

Group of people in a lab talking by a giant computer screen
Group of people in a lab talking by a giant computer screen

Quantum computing makes waves in drug discovery

Alex Generous, PhD

Learn how quantum computing is being used at St. Jude.

A curative gene therapy for Diamond-Blackfan anemia nears the clinic

Alex Generous, PhD

Find how St. Jude researchers are pushing forward a potential cure for DBA.

St. Jude scientists do more with less using PeCan-Seq liquid biopsy

Alex Generous, PhD

Novel plasma test shows promise.

Cre matters: Neuroblastoma oncogene activation controls what type of tumor forms

 Brian O'Flynn, PhD

See how rare pancreatic cancer is triggered in neuroblastoma model

Working from the same playbook to characterize rare sarcoma

 Brian O'Flynn, PhD

See how pooling rhabdomyosarcoma datasets uncovered new insights into the rare pediatric cancer

two men at a whiteboard
two men at a whiteboard

Shared Resources Spotlight: Cytogenetics

Emilia Asante, PhD

The St. Jude Cytogenetics Shared Resource uses advanced imaging techniques to visualize DNA, RNA, and protein interactions within cells.

Your fatty acid delivery is on the way: studying cellular logistics provides disease insights

Paige Brown Jarreau, PhD

A paper from the laboratory of Chi-Lun Chang, PhD, details their new toolkit, FABCON, for detecting contact sites where organelles exchange material.

dali-like illustration of clocks in a wasteland
dali-like illustration of clocks in a wasteland

The ticking ‘epigenetic’ clock measures true biological age

 Alex Generous, PhD

Dive into research on the ‘epigenetic clock’ and learn how understanding it can help childhood cancer survivors.

Two people in white coats examining a slide.
Two people in white coats examining a slide.

Influenza and gene therapy researchers team up to create more effective flu vaccine

 Ashley DuMont, PhD

Graduate students team up to design more effective flu vaccine.

Like kisMET: targeted therapy and radiation synergize in pediatric high-grade glioma

Erin Podolak, MA

Translational research from Suzanne Baker, PhD, and colleagues shows that targeted MET inhibitor capmatinib effectively crosses the blood-brain-barrier, synergizing with radiation to treat pediatric high-grade glioma.