Research
Learn about published research as well as leading-edge basic and translational research initiatives from St. Jude laboratories.
New studies raise warnings with CRISPR-Cas9, but there's more to the story
Recent studies highlight efficacy and safety issues of CRISPR. While the results are important, read why we should wait before drawing conclusions.
All in the family: How 59,000 volunteers and a team of scientists helped uncover six inherited gene mutations for medulloblastoma
There were 110 suspect genes. We found the six that could lead to childhood brain tumors.
New discoveries are simply that and must withstand the test of time
You really trust the ‘latest and greatest?’ Over-hyped scientific discoveries that haven’t been thoroughly tested create false hope for cures.
Statistical hypothesis testing: minimize bias and help ensure your results are significant
Don’t fall for the trap: Follow these 4 steps to help ensure your experimental results are statistically significant.
Hydroxyurea: How much is too much? Sickle cell study reveals individualized dosage leads to decreased hospitalizations
Federally-funded study of hydroxyurea shows that a long-held medication convention isn’t best for pediatric sickle cell patients.
CAR T cells: Are they on the horizon for treatment of solid tumors?
Ongoing research on CAR T-cell therapy, heralded as a miracle cure, shows promise for treating solid tumors. How close are we?
Cells trained to recognize returning infections
The former killers now recognize the enemy when it returns — and you’re better off because of it.
Fat Chance: 'Skinny Gene' research unexpectedly leads to tumor breakthrough
A wrong turn in fat research uncovered an important clue to pinpoint an origin of the most prevalent soft tissue cancer in children.
A hypothesis can’t be right unless it can be proven wrong
Always being right is wrong — Learn how science can be corrupted by poor experiments and theories that cannot be disproven.
Exploring the Sonic Hedgehog pathway – how embryonic cells broadcast their growth instructions
New research of the Sonic Hedgehog pathway shows potential targets for cancer treatments. Read how this cellular pathway plays a critical role in normal and cancerous development.