Research

With a comprehensive approach to thinking about data, St. Jude scientists are fueling progress.

Platform Design, a software package, enables clinicians to add study arms to a clinical trial.

The ADAPT study revealed barriers that stand in the way of palliative care in Latin America.

Research reveals how inherited genetic variants can contribute to liver toxicity after chemotherapy.

St. Jude computational biologists created a computational score predicting cancer drug sensitivity to HDAC6 inhibitors in a promising phase Ib clinical trial.

St. Jude scientists have learned that bacteria are more successful at developing antibiotic resistance when they swap genes through recombination.

St. Jude scientists have created the first model that faithfully recapitulates details of pediatric bone marrow failure.

Microcephaly is a rare neurodevelopmental condition in which a baby’s head is much smaller than expected because the brain did not develop properly or stopped developing during pregnancy. St. Jude researchers identified cells in the outer radial glia in the developing brain that play an important role in microcephaly.

The incidence of pediatric and adult liver cancer is increasing worldwide. Research suggests how premature birth may influence the risk for children.

St. Jude scientists are leading research into the genetics of childhood cancer survivorship to understand and prevent the risk of chronic disease in survivors.