Research

St. Jude computational biologists created a computational score predicting cancer drug sensitivity to HDAC6 inhibitors in a promising phase Ib clinical trial.

St. Jude scientists have learned that bacteria are more successful at developing antibiotic resistance when they swap genes through recombination.

St. Jude scientists have created the first model that faithfully recapitulates details of pediatric bone marrow failure.

Microcephaly is a rare neurodevelopmental condition in which a baby’s head is much smaller than expected because the brain did not develop properly or stopped developing during pregnancy. St. Jude researchers identified cells in the outer radial glia in the developing brain that play an important role in microcephaly.

The incidence of pediatric and adult liver cancer is increasing worldwide. Research suggests how premature birth may influence the risk for children.

St. Jude scientists are leading research into the genetics of childhood cancer survivorship to understand and prevent the risk of chronic disease in survivors.

St. Jude initiative aims to change the outlook for children with catastrophic neurological diseases.

Stimulating the adaptive immune response can improve outcomes for ALL treated with chemotherapy.

St. Jude research has advanced understanding of the immune response to SARS-CoV-2 infection and vaccination. Here is what the findings mean for you.

Muscle signaling provide clues for treatment of the muscle-wasting disorder cachexia, which affects cancer patients.