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PREDSEQ: Identifying Infections Early in Children and Adolescents with Cancer

About this study

Your blood and tissues contain DNA, which serves as the “instruction book” for the cells that make up our bodies. Each person’s DNA is unique. Bacteria, viruses and other infectious organisms also contain DNA and can be identified by finding the unique code for each type.

Researchers in this study want to see if they can detect potential infections by looking at DNA in your blood. Researchers hope the process may reveal new information about how genes interact with other factors to cause disease, affect treatments or the outcome of a disease.

During your cancer treatment, standard blood testing will be done. Researchers will use any leftover blood from these standard tests to run the new, DNA blood test. They will also review your medical history, collect information about the drugs you take and learn about any infections you may develop.

The DNA test is not approved by the U.S. Food and Drug Administration (FDA).

Eligibility overview

  • Younger than 25 years
  • Undergoing cancer therapy at St. Jude Children’s Research Hospital
  • Considered to be at high risk of infection

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The above information is intended to provide only a basic description about a research protocol that may be currently active at St. Jude. The details made available here may not be the most up-to-date information on protocols used by St. Jude. To receive full details about a protocol and its status and or use at St. Jude, a physician must contact St. Jude directly.

Overview

Full title:

Prediction of Adverse Events in Children and Adolescents with Cancer at High Risk of Infection

Study goal:

The main goal of this study is to learn whether new tests to identify DNA in the blood can detect an infection, or risk of relapse, earlier than standard tests.

Age:

Younger than 25 years

Clinical trials categories:

Childhood Cancer Infectious Diseases

For physicians and researchers

Patients accepted to St. Jude must be referred by a physician or other qualified medical professional. Learn how St. Jude can partner with you to care for your patient.

 

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