Research

Learn about published research as well as leading-edge basic and translational research initiatives from St. Jude laboratories.

Researchers share real-time clinical genomics data through St. Jude Cloud platform
Researchers share real-time clinical genomics data through St. Jude Cloud platform

Researchers introduce real-time clinical genomics data using St. Jude Cloud platform at 2019 ASCO annual meeting

Elizabeth Whittington

Scott Newman, PhD, shares the release of real-time clinical genomics data through the St. Jude Cloud platform at the 2019 American Society of Clinical Oncology (ASCO) meeting in Chicago, Illinois.

Researchers develop method to dramatically reduce error rate in next-generation sequencing
Researchers develop method to dramatically reduce error rate in next-generation sequencing

Researchers develop method to dramatically reduce error rate in next-generation sequencing

St. Jude Communications Department

It’s easier to find a needle in a haystack when you take away the hay – read how this research team is reducing gene sequencing errors.

Genetic variations in a fourth gene linked to elevated leukemia risk in Hispanic children
Genetic variations in a fourth gene linked to elevated leukemia risk in Hispanic children

Genetic variations in a fourth gene linked to elevated leukemia risk in Hispanic children

Jun Yang, PhD

Read how ancestry plays a role in determining your risk for cancer. In the case of Hispanic children, researchers found an increased risk of leukemia.

Gene therapy: Scientific breakthrough and a legacy of a cure
Gene therapy: Scientific breakthrough and a legacy of a cure

Gene therapy: Scientific breakthrough and a legacy of a cure

James R. Downing, MD

Read about the work from a goal – to a treatment – to a cure – and one scientist’s legacy.

Pediatric melanoma mystery solved by genome sequencing research
Pediatric melanoma mystery solved by genome sequencing research

Pediatric melanoma mystery solved by genome sequencing research

Scott Newman, PhD

Two pediatric melanoma cases diagnosed a year apart reveal a new genetic driver of the disease. Read more about this spitzoid melanoma work.

Bioinformatics research scientist helps unlock elusive data
Bioinformatics research scientist helps unlock elusive data

From evolutionary biology to immunology via bioinformatics

Gary Bridgman

Immunologists turn to Jeremy Crawford, PhD, when planning complex experiments or re-analyzing collected data. Learn about his bioinformatics career.

Researchers identify new necroptosis triggers
Researchers identify new necroptosis triggers

Researchers identify new molecular triggers for cell’s 'executioner'

Chris Pennington

Read how this molecule rips the “skin” of the cell to kill it, and how research is learning how this power is unleased.

What hidden hazards lie beneath the surface of genome editing?
What hidden hazards lie beneath the surface of genome editing?

What hidden hazards lie beneath the surface of genome editing?

Keith Crabtree, PhD

Are you sure? Understanding the possible traps and dangers with gene editing.

Commitment to excellence: Building a world-class Structural Biology Department at St. Jude
Commitment to excellence: Building a world-class Structural Biology Department at St. Jude

Commitment to excellence: Building a world-class Structural Biology Department at St. Jude

Charalampos Kalodimos, PhD

Read how this rapidly evolving area of science seeks to change the way we look at the world.

Cell Seek provides a path to understanding the cellular origins of brain tumors
Cell Seek provides a path to understanding the cellular origins of brain tumors

Cell Seek provides a path to understanding the cellular origins of pediatric brain tumors

Lee Morgan

What if scientists shared data about brain development to find the origins of brain tumors and disorders? These scientists did, and it changed everything.