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Recruiting

SNIFF: Determinants of Disease Severity in Influenza Infection

About this study

Influenza viruses (flu viruses) cause many severe respiratory illnesses across the world. The symptoms and how bad the illness gets can vary greatly. Some children with flu have mild, cold-like symptoms. Other children have more severe disease that needs pediatric intensive care unit management or even results in death.

Compared to adults, as many as half of all children who go to the hospital for flu have no known risk factors. The purpose of this study is to learn more about why some children and young adults develop severe flu infection while others do not.

During this study, you will have about 4 in-person study visits and 6 study phone calls for up to 2 years.

  • During your in-person visits, we will:
    • Collect blood and nasal swab samples. No more than 7 mL (about 2.5 teaspoons) of blood will be collected at each visit.
    • Collect details about your medical history and medicines.
  • During your phone call visits, we will:
    • Ask you about updates to your medical history and medicines. We may ask you if you missed any days of work due to being sick.

Eligibility overview

  • Less than 30 years old
  • Diagnosed with flu or has suspected flu infection

The above information is intended to provide only a basic description about a research protocol that may be currently active at St. Jude. The details made available here may not be the most up-to-date information on protocols used by St. Jude. To receive full details about a protocol and its status and or use at St. Jude, a physician must contact St. Jude directly.

Overview

Full title:

SNIFF: Determinants of Disease Severity in Influenza Infection

Study goal:

To learn more about why some children and young adults get very sick with flu while others do not.

Diagnosis:

Flu or suspected flu

Age:

Less than 30 years old

Clinical trials categories:

Infectious Diseases

For physicians and researchers

Patients accepted to St. Jude must be referred by a physician or other qualified medical professional. Learn how St. Jude can partner with you to care for your patient.

 

Learn more