Research

Learn about published research as well as leading-edge basic and translational research initiatives from St. Jude laboratories.

Searching for answers to rare cancers in the TP53 gene
Searching for answers to rare cancers in the TP53 gene

TP53: One important gene in rare cancers - an update

Emilia Modolo Pinto, PhD

St. Jude clinicians and researchers seek answers to some of the rarest pediatric tumors and diseases, including adrenocortical tumors. Read more about their work uncovering the TP53 gene.

Cloud redesign offers enhanced user experience
Cloud redesign offers enhanced user experience

Cloud redesign offers enhanced user experience

Clay McLeod

Read how this redesign offers computational scientists an edge when it comes to genomics and other omics.

Collaborating on SARS-CoV-2 and pediatric cancer
Collaborating on SARS-CoV-2 and pediatric cancer

Collaborating on SARS-CoV-2 and pediatric cancer

Miguela Caniza, MD, MPH

This collaboration on infection prevention pivoted early in the SARS-CoV-2 pandemic and did this global pediatric cancer community.

A vaccine to prevent ear infections? Here’s the latest
A vaccine to prevent ear infections? Here’s the latest

A vaccine to prevent ear infections? Here’s the latest.

Mary Powers

Almost everyone gets ear infections. This vaccine may change that.

A global resource to learn more about pediatric cancer patients and COVID-19
A global resource to learn more about pediatric cancer patients and COVID-19

A global resource to learn more about pediatric cancer patients and COVID-19

Nickhill Bhakta, MD, MPH

Little is known about childhood cancer patients who are diagnosed with COVID-19, but a new registry is the first step to finding out.

Researchers take the fight to drug resistance up an octave
Researchers take the fight to drug resistance up an octave

Researchers take the fight to drug resistance up an octave

Robert J. Autry and William E. Evans, PharmD

Drug resistance is a major reason for treatment failure in children with leukemia, but recent research may have an answer.

Learning more about T cells through studying behavior in Type 1 diabetes
Learning more about T cells through studying behavior in Type 1 diabetes

Learning more about T cells through studying behavior in Type 1 diabetes

Ben Youngblood, PhD

Learning more about how the body attacks itself in Type 1 diabetes offers insights into how to harness the power of T cells to treat cancer.

Discovery shows oxygen’s role in neuron development
Discovery shows oxygen’s role in neuron development

Discovery shows oxygen’s role in neuron development

David J. Solecki, PhD

Read how oxygen’s role neuron development is critical for brain health in infants.

Pushing the limits to find relationship between proteomics and Alzheimer’s
Pushing the limits to find relationship between proteomics and Alzheimer’s

Pushing the limits to find relationship between proteomics and Alzheimer’s

Mary Powers

Read how a 20-year wait for technology shows key insights in brain proteins’ role in the development and progression of Alzheimer’s.

Microscopes: Paths and barriers to discovery and super resolution
Microscopes: Paths and barriers to discovery and super resolution

Microscopes: Paths and barriers to discovery and super resolution

David J. Solecki, PhD

Combining microscopes allows for a resolution that allows scientists to see deep into a cell and how neurons organize gene expression in cell formation.