Research

Learn about published research as well as leading-edge basic and translational research initiatives from St. Jude laboratories.

Protein Science cover
Protein Science cover

It’s the little things that count – so let’s count the little things

Brian O'Flynn, PhD

Scientists in the Fischer lab are developing tools to explore new aspects of protein structure and function.

Image of mouse heart using Cell and Tissue Imaging Center's technology to see within tissue.
Image of mouse heart using Cell and Tissue Imaging Center's technology to see within tissue.

Shared Resource Spotlight: Cell and Tissue Imaging Center

Akshita Bhatt, PhD

The Cell and Tissue Imaging Center helps fuel breakthroughs using light and electron microscopy.

RSV illustration
RSV illustration

Ramilo brings RSV expertise to St. Jude

Alex Generous, PhD

Discover Ramilo's plans for St. Jude RSV research.

Cancer on planet illustration
Cancer on planet illustration

Metastatic cancer cells thrive in harsh microenvironments

Erin Podolak, MA

Like a journey through space, metastatic cells have to adapt to spread throughout the body.

Data driven progress illustration
Data driven progress illustration

Data-driven science helps researchers design new protein interactions

Erin Podolak, MA

With a comprehensive approach to thinking about data, St. Jude scientists are fueling progress.

Xiaomeng Yuan, PhD, and Haitao Pan, PhD
Xiaomeng Yuan, PhD, and Haitao Pan, PhD

Biostatisticians are key to getting therapies to patients faster

Xiaomeng Yuan, PhD and Haitao Pan, PhD

Platform Design, a software package, enables clinicians to add study arms to a clinical trial.

Michael McNeil, MD, MPH
Michael McNeil, MD, MPH

Global palliative care requires on-the-ground understanding

Michael J. McNeil, MD

The ADAPT study revealed barriers that stand in the way of palliative care in Latin America.

Lab table
Lab table

Liver toxicity and ALL: Genomics drive variability between patients

Erin Podolak, MA

Research reveals how inherited genetic variants can contribute to liver toxicity after chemotherapy.

Qingfei Pan and Jiyang Yu
Qingfei Pan and Jiyang Yu

Math test points metastatic breast cancer treatment in the right direction

Alex Generous, PhD

St. Jude computational biologists created a computational score predicting cancer drug sensitivity to HDAC6 inhibitors in a promising phase Ib clinical trial.

Scientist in lab wearing gloves and with bunsen burner on
Scientist in lab wearing gloves and with bunsen burner on

On the road to resistance: How bacteria can win the game of life ‘with a little help from their friends’

Erin Podolak, MA

St. Jude scientists have learned that bacteria are more successful at developing antibiotic resistance when they swap genes through recombination.