Research

Learn about published research as well as leading-edge basic and translational research initiatives from St. Jude laboratories.

What hidden hazards lie beneath the surface of genome editing?
What hidden hazards lie beneath the surface of genome editing?

What hidden hazards lie beneath the surface of genome editing?

Keith Crabtree, PhD

Are you sure? Understanding the possible traps and dangers with gene editing.

Commitment to excellence: Building a world-class Structural Biology Department at St. Jude
Commitment to excellence: Building a world-class Structural Biology Department at St. Jude

Commitment to excellence: Building a world-class Structural Biology Department at St. Jude

Charalampos Kalodimos, PhD

Read how this rapidly evolving area of science seeks to change the way we look at the world.

Cell Seek provides a path to understanding the cellular origins of brain tumors
Cell Seek provides a path to understanding the cellular origins of brain tumors

Cell Seek provides a path to understanding the cellular origins of pediatric brain tumors

Lee Morgan

What if scientists shared data about brain development to find the origins of brain tumors and disorders? These scientists did, and it changed everything.

10,000 reasons St. Jude Cloud can help advance science

Chris Pennington

10,000 reasons St. Jude Cloud can help advance science

Medulloblastoma therapy may get better thanks to key technology
Medulloblastoma therapy may get better thanks to key technology

Medulloblastoma therapy may get better thanks to ‘key’ technology

Martine F. Roussel, PhD

In testing a new treatment for a deadly brain tumor, read what these researchers did to figure out how to make exact duplicates of the cancer.

Innate immunity: the body’s first line of defense against a dangerous fungus
Innate immunity: the body’s first line of defense against a dangerous fungus

Innate immunity: the body’s first line of defense against a dangerous fungus

Thirumala-Devi Kanneganti, PhD

Innate immunity is your body’s first line of defense. What happens when it’s weakened? Researchers are using this common fungus to find out how to help.

Medulloblastoma and microirradiation: Tiny treatments for the most common malignant pediatric brain tumor
Medulloblastoma and microirradiation: Tiny treatments for the most common malignant pediatric brain tumor

Medulloblastoma and microirradiation: Tiny treatments for the most common malignant pediatric brain tumor

Martine F. Roussel, PhD

Medulloblastoma may soon be treated by a microirradiator - a machine the size of two refrigerators that beams radiation down to half the width of a credit card.

Translational research: Seeing what we do and who we help
Translational research: Seeing what we do and who we help

Translational research: Finding the connection between what we do and who we help

Himy Muniz-Talavera, PhD

It's a rare day you get to see translational research benefit others—I've spoken to cancer patients and seen first-hand how research saves children's lives.

Computational algorithm fix restores power to research
Computational algorithm fix restores power to research

Computational algorithm fix restores power to research

Jiyang Yu, PhD

A computational algorithm helps analyze large data sets at the expense of computing power. This small fix to a free program brings big data back to small labs.

Neural development: Unlikely partners work together to make your brain: when they don’t get along, it could lead to rare and devastating disease
Neural development: Unlikely partners work together to make your brain: when they don’t get along, it could lead to rare and devastating disease

Neural development: Unlikely partners work together to make your brain: when they don’t get along, it could lead to rare and devastating disease

Jamy Peng, PhD

In neural development, two essential molecules partner to build the human brain — but when things go awry, it could lead to brain cancer.