Author Profile

Heather Mefford, MD, PhD

Faculty, Department of Cell & Molecular Biology

Heather Mefford, MD, PhD

Heather Mefford, MD, PhD, is a faculty member in the Department of Cell & Molecular Biology at St. Jude.

Stories by Heather Mefford

Discovering how T cell 'exhaustion' is triggered could energize cancer immunotherapy
Discovering how T cell 'exhaustion' is triggered could energize cancer immunotherapy
Research

Discovering how T cell “exhaustion” is triggered could energize cancer immunotherapy

Ben Youngblood, PhD

Read how the discovery of this gene could change immunotherapy cancer and viral infection treatments.

‘Black hole’ of cancer journey? Transition oncology fills that gap
‘Black hole’ of cancer journey? Transition oncology fills that gap
Clinical

‘Black hole’ of cancer journey? Transition oncology program fills the gap

Keith Crabtree, PhD

You’re just out of cancer treatment – now what? Read about the transition oncology program that helps young cancer patients get back to living.

Enzymes that unlock stress granules, our cells’ biological ‘storm shelters,’ open pathway to treating muscle, brain disorders
Enzymes that unlock stress granules, our cells’ biological ‘storm shelters,’ open pathway to treating muscle, brain disorders
Research

Enzymes that unlock stress granules, our cells’ biological ‘storm shelters,’ open pathway to treating muscle, brain disorders

Mondira Kundu, MD, PhD

Stress granules form from heat shock to the cell then disappear, but when treated with an inhibitor to the protein ULK, the stress granules persist event after removal of the stress.

Length matters in dipeptide repeat polypeptides – and can be a way to treat ALS
Length matters in dipeptide repeat polypeptides – and can be a way to treat ALS
Research

Length matters in dipeptide repeat polypeptides – and can be a way to treat ALS

Richard Kriwacki, PhD

Read how the length of these proteins may be an indicator of ALS.

Treatment strategies matter in childhood ALL survivorship
Treatment strategies matter in childhood ALL survivorship
Research

Exploring survivorship: The when and how of treatment strategies matter in adult survivors of childhood ALL

Mike O’Kelly

It used to be just about surviving–now, it’s about treating children with ALL to live long, healthy lives. Learn about ALL survivorship research from ASCO.

Having trouble reading? Hearing loss could be part of the problem
Having trouble reading? Hearing loss could be part of the problem
Clinical

Having trouble reading? Hearing loss could be part of the problem

Heather Conklin, PhD

There’s a link between hearing loss and difficulty learning to read – and researchers are looking into helping young brain tumor survivors bolster their reading skills.

Researchers share real-time clinical genomics data through St. Jude Cloud platform
Researchers share real-time clinical genomics data through St. Jude Cloud platform
Research

Researchers introduce real-time clinical genomics data using St. Jude Cloud platform at 2019 ASCO annual meeting

Elizabeth Whittington

Scott Newman, PhD, shares the release of real-time clinical genomics data through the St. Jude Cloud platform at the 2019 American Society of Clinical Oncology (ASCO) meeting in Chicago, Illinois.

Collaboration is the key to fighting childhood cancer worldwide
Collaboration is the key to fighting childhood cancer worldwide
Outreach

Collaboration is the key to fighting childhood cancer worldwide

Carlos Rodriguez-Galindo, MD

The biggest factor in childhood cancer survival is where you’re born. This group is doing something to ensure that doesn’t matter.

Resources, collaboration: two components of great research
Resources, collaboration: two components of great research
Outreach

Resources, collaboration: two components of great research

Jennifer Parris

Read how this woman coordinates and sometimes invents resources at this top research facility to help scientists doing critical work.

Researchers develop method to dramatically reduce error rate in next-generation sequencing
Researchers develop method to dramatically reduce error rate in next-generation sequencing
Research

Researchers develop method to dramatically reduce error rate in next-generation sequencing

St. Jude Communications Department

It’s easier to find a needle in a haystack when you take away the hay – read how this research team is reducing gene sequencing errors.