St. Jude Research

2024 Archive

Graphic depicting infant vaccination
Graphic depicting infant vaccination
Research

Exploring the interplay between vaccines and immune system development in infants

 Brian O'Flynn, PhD

Explore new research delving into pediatric immune responses to vaccination

Graphic depicting two hands and a globe
Graphic depicting two hands and a globe
Outreach

St. Jude Global builds pathology and laboratory medicine capacity and community

Alex Generous, PhD

The St. Jude Global Pathology and Laboratory Medicine Transversal aims to improve diagnostic testing worldwide.

Francesca Ferrara, PhD
Francesca Ferrara, PhD
Clinical

Shared Resource Spotlight: St. Jude Vector Laboratory (SJVL)

Emilia Asante, PhD

The St. Jude Vector Laboratory advances gene therapy through viral vectors, advancing scientific and therapeutic innovation.

Nickhill Bhakta and Nancy Bolous
Nickhill Bhakta and Nancy Bolous
Outreach

Bridging the pediatric cancer budgeting gap in national cancer control plans

Alex Generous, PhD

A new rapid budgeting tool increases the likelihood pediatric cancer will be included in national cancer control plans globally.

Investigator Insights

5 Questions for Laura Jolovic

 Erin Podolak, MA and Laura Jolovic

Meet St. Jude radiation therapist Laura Jolovic and learn how she provides care for children with cancer as well as mentors students interested in a career in pediatric radiation oncology.

3 men in a lab
3 men in a lab
Research

CRISPR kickstarts combination drug discovery for neuroblastoma

Alex Generous, PhD

A CRISPR screen reveals a potential combination therapy for relapsed neuroblastoma.

Outreach

Building blocks: St. Jude Global guides reestablishment of health care capacity during crisis

Erin Podolak, MA

St. Jude Global helps provide a framework for rebuilding health care capacity after a crisis.

Research

Finding the big-TIME players holding back CAR T–cell therapy for high-grade gliomas

 Alex Generous, PhD

Explore how tumor-associated macrophages shape CAR T-cell therapy efficacy in high-grade gliomas.

Alaa Refaat, PhD
Alaa Refaat, PhD
Investigator Insights

5 Questions for Alaa Refaat

 Erin Podolak, MA and Alaa Refaat, PhD

Meet St. Jude senior scientist Alaa Refaat, PhD, and learn about his work to develop treatments for childhood brain tumors using chemical biology approaches.

(L to R) First author Prahalathan Pichavaram, PhD, corresponding author Andrew Murphy, MD, St. Jude Department of Surgery and co-author Carolyn Jablonowski, PhD.
(L to R) First author Prahalathan Pichavaram, PhD, corresponding author Andrew Murphy, MD, St. Jude Department of Surgery and co-author Carolyn Jablonowski, PhD.
Research

Ribosome production presents a new therapeutic opportunity against Wilms tumor

 Alex Generous, PhD

Discover how disruption ribosomes creation provides promise for “undruggable” cancers.