Experimental Cellular Therapeutics Laboratory

The mission of the ECTL is to help St. Jude investigators develop clinical grade manufacturing processes in close collaboration with the St. Jude GMP facility. The Laboratory is focused primarily on:

1. Develops processes and provides services for clinical scale purification, engineering, genetic modification, expansion, and cryopreservation of cells
2. Generates relevant data, prepares documents to support Investigational New Drug (IND) applications to the FDA
3. Develops, Identifies, introduces, and validates new technologies to facilitate and improve processes for manufacturing cellular therapeutics.

The ECTL has five senior researchers, each holding a Ph.D. degree in biological or medical sciences with over ten years of post-degree laboratory research experience. All ECTL researcher undergo cGMP training conducted by the quality assurance team of GMP and actively engage in weekly cell and gene therapy meetings alongside clinical and laboratory-based investigators and GMP personnel. These collaborative efforts streamline the effective development and seamless transfer of the manufacturing processes for novel cellular products to the GMP for production.