Center for In Vivo Imaging and Therapeutics (CIVIT)

The mission of the Center for In Vivo Imaging and Therapeutics (CIVIT) is to facilitate the use of cutting-edge imaging and image-guided therapy technologies to advance the research of St. Jude investigators. The CIVIT is staffed by PhD-level scientists for consultation and experimental design and highly skilled Research Technologists to provide imaging, surgery, and preclinical therapeutic services. Preclinical imaging modalities include bioluminescence imaging (BLI), high resolution ultrasound (US), intravital multiphoton microscopy, magnetic resonance imaging (MRI), micro-computed tomography (µCT), positron emission tomography (PET), and image-guided radiation therapy (IGRT) Imaging (MRI, PET/CT, BLI, US, intravital microscopy) and surgical procedures are conducted within a barrier housing facility, facilitating studies utilizing severely immunocompromised models.

CIVIT enables St. Jude investigators to conduct high-density, complex preclinical studies at reasonable cost with expert input. CIVIT supports the work of investigators across the institution and has been acknowledged as a contributor on almost 200 peer-reviewed publications.