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Childhood Solid Tumor Network

Research Publications

Brady SW, Ma X, Bahrami A, et al. The clonal evolution of metastatic osteosarcoma as shaped by cisplatin treatment. Mol Cancer Res 17(4):895-906, 2019.
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Loh AHP, Stewart E, Bradley CL, et al. Combinatorial screening using orthotopic patient derived xenograft-expanded early phase cultures of osteosarcoma identify novel therapeutic drug combinations. Cancer Lett 442:262-270, 2019.
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Stewart E, McEvoy J, Wang H, et al. Identification of Therapeutic Targets in Rhabdomyosarcoma through Integrated Genomic, Epigenomic, and Proteomic Analyses. Cancer Cell 34(3):411-426, 2018.
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Stewart E, Federico S, Karlstrom A, et al. The Childhood Solid Tumor Network: A new resource for the developmental biology and oncology research communities. Dev Biol 411(2):287-293, 2016.
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Stewart E, Shelat A, Bradley C, et al. Development and characterization of a human orthotopic neuroblastoma xenograft. Dev Biol 407(2):344-355, 2016.
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Pinto EM, Chen X, Easton J, et al. Genomic landscape of paediatric adrenocortical tumours. Nat Commun 6:6302, 2015.
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Lu C, Zhang J, Nagahawatte P, et al. The genomic landscape of childhood and adolescent melanoma. J Invest Dermatol 135(3):816-823, 2015.
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Stewart E, Gosham R, Bradley C, et al. Targeting the DNA Repair Pathway in Ewing Sarcoma. Cell Rep 9(3):829-841, 2014.
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Tirode F, Surdez D, Ma X, et al. Genomic landscape of Ewing sarcoma defines an aggressive subtype with co-association of STAG2 and TP53 mutations. Cancer Discov 4(11):1342-1353, 2014. 
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Chen X, Bahrami A, Pappo A, et al. Recurrent somatic structural variations contribute to tumorigenesis in pediatric osteosarcoma. Cell Rep 7(1):104-112, 2014.
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Chen X, Stewart E, Shelat A, et al. Targeting oxidative stress in embryonal rhabdomyosarcoma. Cancer Cell 24(6):710-724, 2013.
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Cheung NK, Zhang J, Lu C, et al. Association of age at diagnosis and genetic mutations in patients with neuroblastoma. JAMA 307(10):1062-1071, 2012. 
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Zhang J, Benavente CA, McEvoy J, et al. A novel retinoblastoma therapy from genomic and epigenetic analyses. Nature 481(7381):329-334, 2012.
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