2021 Archive

Profiles

5 Questions for Xin-yan Chen, PhD

LaToyia P. Downs, PhD and Xin-yan Chen

Meet postdoctoral researcher Xin-yan Chen, PhD, Department of Tumor Cell Biology, and learn about her research.  

Outreach

Global Platform builds momentum for improving childhood cancer care

Alex Generous, PhD

Find out how the Global Platform is forming the foundation of systemic improvements in multiple countries.

Clinical Research

Understanding best friendships and psychosocial health in pediatric brain tumor survivors

Kathryn J. McCullough, MA

Learn how researchers examined the impact of friendships on social functioning in pediatric brain tumor survivors.

Research

Combination therapy research strategy comes full circle

Brian O'Flynn, PhD

See how drug activity, not drug synergy should guide preclinical drug combination discovery such as for leukemia including antagonistic drug combos

Profiles

5 Questions for Jingjing Chen, PhD

LaToyia P. Downs, PhD and Jingjing Chen

Meet postdoctoral researcher Jingjing Chen, PhD, Department of Hematology, and learn about her research.

Outreach

Learning today to become the mentors of tomorrow

LaToyia P. Downs, PhD

Learn more about how mentorship at St. Jude prepares future leaders in research and medicine.

Research

Death-defying mechanism drives premature aging in blood stem cells after transplant

Alex Generous, PhD

Discover how mitochondria help stem cells re-establish the blood system at the cost of accelerated aging.

Clinical Research

Multidimensional insights guide treatment for pediatric diffuse hemispheric glioma

LaToyia P. Downs, PhD

See how new research is guiding the best treatment strategies to improve outcomes in pediatric diffuse hemispheric glioma.

Profiles

5 Questions for Sarada Achyutuni, PhD

LaToyia P. Downs, PhD and Sarada Achyutuni

Meet postdoctoral researcher Sarada Achyutuni, PhD, Center of Excellence for Leukemia Studies, and learn about her research.

Leukemia

AI-driven μPharma platform accurately predicts leukemia drug sensitivity

Brian O'Flynn, PhD

See how an artificial intelligence single-cell microfluidics pharmacotyping tool helps identify drugs for T-cell acute lymphoblastic leukemia

Research

Pain may be a risk factor for learning problems in childhood cancer survivors

Mary Powers

Researchers are focusing on treatment-related pain as another way to reduce the risk of learning and memory problems in survivors of childhood leukemia.

About St. Jude

Rising Stars of Cancer Research lectures to bring fresh insights

Mary Powers

The Rising Stars of Cancer Research program is a new to the Science of Childhood Cancer lecture series. The program highlights the work of emerging leaders in the cancer research community.

Global Health

St. Jude Global Alliance holds third annual convening

Lance Wiedower

Empower Everyone was the theme of the St. Jude Global Alliance Convening, a virtual meeting that attracted participants from around the world.

Research

CoNGA: Deciphering the dance of T-cell differentiation

Stefan Schattgen, PhD

St. Jude scientists have created an algorithm to help group T-cells by their function by evaluating two different types of data, T-cell receptor sequences and gene expression.

HIV

St. Jude mourns the death of infectious diseases pioneer Walter Hughes, MD

Mike O’Kelly

Walter Hughes, MD, who established the St. Jude Department of Infectious Diseases and initiated pediatric AIDS research at the hospital, has died.

Clinical Research

St. Jude biostatisticians create a novel clinical trial design software

St. Jude Progress

St. Jude biostatisticians have developed a new method for designing phase 2 clinical trials with a small sample size. The approach uses a mathematical model called Bayesian probability . The researchers created free software to implement the process.

Research

Bringing Chemistry to Medicine: Transcription therapy symposium is set for July 22 and 23

Mike O’Kelly

St. Jude will host the virtual Bringing Chemistry to Medicine Symposium July 22–23. The inaugural event in 2020 prompted a researcher in India to become a visiting scientist at St. Jude. Register for the event.

Clinical Research

When work takes a toll: St. Jude research adds to our understanding of physician burnout.

Jonathan Burlison and Lindsay Blazin

St. Jude researchers looked at burnout and perceived work demands among St. Jude physicians and found that emotional exhaustion and time demands are key factors in a problem that affects both provider and patient.

Profiles

Connections with colleagues: A St. Jude pediatric psychologist has renewed appreciation for an overlooked benefit of interdisciplinary collaboration.

Elyse Heidelberg, PsyD

A pediatric psychologist expresses gratitude for interdisciplinary collaboration, which elevates patient care and provider well-being.

Cancer Biology

Roussel’s early discovery shaped a career of cancer research

St. Jude Communications Department

Martine Roussel, PhD, faculty member and endowed chair in molecular oncogenesis, shares how early work on oncogenes led to her lab’s discovery of new oncogenes.