2021 Archive

St. Jude On

Hemoglobin research comes of age to revolutionize β-thalassemia treatment

Brian O'Flynn, PhD

Learn about the efforts to address this blood disorder

Research

Following one unexplained case to a new rare bone marrow failure disorder causing high p53 levels

Alex Generous, PhD

Learn what St. Jude physicians do when confronted with a new, unknown blood disorder.

Investigator Insights

Pioneering human brain model systems

Anjana Nityanandam, PhD

Meet Anjana Nityanandam, PhD, founder and director of the Human Neural Organoid Laboratory (HNOL) at St. Jude, a lab that pioneers the use of human brain model systems in research.

Investigator Insights

5 Questions for Alexander Ciurej, MD

Alexander Ciurej, MD and Heather Johnson

Find out what led pediatric hematology-oncology fellow Alexander Ciurej, MD, to St. Jude and how he’s expanding his abilities as a clinical researcher through the Graduate School.

Research

Seeing neurobiology at every scale

Alex Generous, PhD

See how the Neuroimaging Laboratory enables St. Jude microscopy.

Investigator Insights

5 Questions for Yuliana Díaz Tirado

Heather Johnson and Yuliana Diaz Tirado

Meet St. Jude Graduate School of Biomedical Sciences PhD student Yuliana Díaz Tirado.

Research

Noninvasive, label-free tissue imaging offers less alteration, more information

Brian O'Flynn, PhD

Learn about the huge potential of noninvasive microscopy

Outreach

Taking steps toward nursing excellence worldwide

LaToyia P. Downs, PhD

See how the St. Jude Global Nursing Transversal Program strengthens pediatric oncology nursing and improves care for children worldwide.

Clinical

A doctor and a mom: Navigating life as both St. Jude physician and patient parent

Alex Generous, PhD

Meet Deena Levine, MD, and her son Eli, who are navigating being a patient family at her workplace.

Research

Shared Resource Spotlight: Center for Bioimage Informatics

Alex Generous, PhD

Meet the Center for Bioimaging Informatics staff to learn how they collaborate with scientists to get more from imaging.

Research

Pain may be a risk factor for learning problems in childhood cancer survivors

Mary Powers

Researchers are focusing on treatment-related pain as another way to reduce the risk of learning and memory problems in survivors of childhood leukemia.

Investigator Insights

Rising Stars of Cancer Research lectures to bring fresh insights

Mary Powers

The Rising Stars of Cancer Research program is a new to the Science of Childhood Cancer lecture series. The program highlights the work of emerging leaders in the cancer research community.

Outreach

St. Jude Global Alliance holds third annual convening

Lance Wiedower

Empower Everyone was the theme of the St. Jude Global Alliance Convening, a virtual meeting that attracted participants from around the world.

Research

CoNGA: Deciphering the dance of T-cell differentiation

Stefan Schattgen, PhD

St. Jude scientists have created an algorithm to help group T-cells by their function by evaluating two different types of data, T-cell receptor sequences and gene expression.

Investigator Insights

St. Jude mourns the death of infectious diseases pioneer Walter Hughes, MD

Mike O’Kelly

Walter Hughes, MD, who established the St. Jude Department of Infectious Diseases and initiated pediatric AIDS research at the hospital, has died.

Research

St. Jude biostatisticians create a novel clinical trial design software

St. Jude Progress

St. Jude biostatisticians have developed a new method for designing phase 2 clinical trials with a small sample size. The approach uses a mathematical model called Bayesian probability . The researchers created free software to implement the process.

Research

Bringing Chemistry to Medicine: Transcription therapy symposium is set for July 22 and 23

Mike O’Kelly

St. Jude will host the virtual Bringing Chemistry to Medicine Symposium July 22–23. The inaugural event in 2020 prompted a researcher in India to become a visiting scientist at St. Jude. Register for the event.

Clinical

When work takes a toll: St. Jude research adds to our understanding of physician burnout.

Jonathan Burlison and Lindsay Blazin

St. Jude researchers looked at burnout and perceived work demands among St. Jude physicians and found that emotional exhaustion and time demands are key factors in a problem that affects both provider and patient.

Investigator Insights

Connections with colleagues: A St. Jude pediatric psychologist has renewed appreciation for an overlooked benefit of interdisciplinary collaboration.

Elyse Heidelberg, PsyD

A pediatric psychologist expresses gratitude for interdisciplinary collaboration, which elevates patient care and provider well-being.

Investigator Insights

Roussel’s early discovery shaped a career of cancer research

St. Jude Communications Department

Martine Roussel, PhD, faculty member and endowed chair in molecular oncogenesis, shares how early work on oncogenes led to her lab’s discovery of new oncogenes.