Selected Publications
Yamada Y, Zheng Z, Jad AK, Yamashita M. Lethal and sublethal effects of programmed cell death pathways on hematopoietic stem cells. Exp Hematol 2024 Apr 4;134:104214.
Rubio-Lara JA, Igarashi KJ, Sood S, Johansson A, Sommerkamp P, Yamashita M, Lin DS. Expanding hematopoietic stem cell ex vivo: recent advances and technical considerations. Exp Hematol 2023 SepOct;125-126:6-15.
Nakajima-Takagi Y, Oshima M, Takano J, Koide S, Itokawa N, Uemura S, Yamashita M, Andoh S, Aoyama K, Isshiki Y, Shinoda D, Saraya A, Arai F, Yamaguchi K, Furukawa Y, Koseki H, Ikawa T, Iwama A. Polycomb repressive complex 1.1 coordinates homeostatic and emergency myelopoiesis. Elife 2023 Jun 2;12:e83004.
Johansson A*, Lin DS*, Mercier FE*, Yamashita M*, Divangahi M, Sieweke MH. Trained immunity and epigenetic memory in long-term self-renewing hematopoietic cells. Exp Hematol 2023 May;121:6- 11. (*equally contributed)
Uemura S, Yamashita M, Aoyama K, Yokomizo-Nakano T, Oshima M, Nishio M, Masuko M, Takizawa J, Sone H, Yamada Y, Suzuki A , Iwama A. YAP1/TAZ activity maintains vascular integrity and organismal survival. Biochem Biophys Res Commun 619:117-123, 2022.
Yamashita M*, Iwama A. Aging and Clonal Behavior of Hematopoietic Stem Cells. Int J Mol Sci 23, 1948; https://doi.org/10.3390/ijms23041948, 2022. (*corresponding author)
Kuribayashi W, Oshima M, Itokawa N, Koide S, Nakajima-Takagi Y, Yamashita M, Yamazaki S, Rahmutulla B, Miura F, Ito T, Kaneda A, Iwama A. Limited rejuvenation of aged hematopoietic stem cells in young bone marrow niche. J Exp Med 218: e20192283, 2021.
Kayamori K, Nagai Y, Zhong C, Kaito S, Shinoda D, Koide S, Kuribayashi W, Oshima M, NakajimaTakagi Y, Yamashita M, Mimura N, Becker H, Izawa K, Yamazaki S, Iwano S, Miyawaki A, Ito R, Tohyama K, Lennox W, Sheedy J, Weetall M, Sakaida E, Yokote K, Iwama A. DHODH inhibition synergizes with DNA-demethylating agents in the treatment of myelodysplastic syndromes. Blood Advances 5:438-450, 2021.
Yang C, Yamashita M, Suda T. A Novel Function of Sphingolipid Signaling via S1PR3 in Hematopoietic and Leukemic Stem Cells. Blood Cancer Discov 2:3-5, 2020.
Yamashita M, Suda T. Low-dose X-rays leave scars on human hematopoietic stem and progenitor cells: the role of reactive oxygen species. Haematologica 105: 1986-1988, 2020.
Yamashita M*, Dellorusso PV*, Olson OC* and Passegué E. Dysregulated haematopoietic stem cell behaviour in myeloid leukaemogenesis. Nat. Rev Cancer doi: 10.1038/s41568-020-0260-3, 2020. (*equally contributed)
Yamashita M and Passegué E. TNF-α Coordinates Hematopoietic Stem Cell Survival and Myeloid Regeneration. Cell Stem Cell 25: 357-372, 2019.
Yamashita M, Nitta E and Suda T. Regulation of hematopoietic stem cell integrity through p53 and its related factors. Ann N Y Acad Sci 1370: 45-54, 2016.
Yamashita M, Nitta E and Suda T. Aspp1 Preserves Hematopoietic Stem Cell Pool Integrity and Prevents Malignant Transformation. Cell Stem Cell 17: 23-34, 2015.
Yamashita M, Nitta E, Nagamatsu G, Ikushima YM, Hosokawa K, Arai F and Suda T. Nucleostemin is indispensable for the maintenance and genetic stability of hematopoietic stem cells. Biochem Biophys Res Commun 441: 196-201, 2013.
Nitta E, Yamashita M, Hosokawa K, Xian M, Takubo K, Arai F, Nakada S and Suda T. Telomerase reverse transcriptase protects ATM-deficient hematopoietic stem cells from ROS-induced apoptosis through a telomere-independent mechanism. Blood 117: 4169-4180, 2011.
Last update: July 2024