Selected Publications
Su Y, Carter JL, Li X, Fukuda Y, Gray A, Lynch J, Edwards H, Ma J, Schreiner P, Polin L, Kushner J, Dzinic SH, Buck SA, Pruett-Miller SM, Hege-Hurrish K, Robinson C, Qiao X, Liu S, Wu S, Wang G, Li J, Allen JE, Prabhu VV, Schimmer AD, Joshi D, Kalhor-Monfared S, Watson IDG, Marcellus R, Isaac MB, Al-Awar R, Taub JW, Lin H, Schuetz JD, Ge Y. The Imipridone ONC213 Targets α-Ketoglutarate Dehydrogenase to Induce Mitochondrial Stress and Suppress Oxidative Phosphorylation in Acute Myeloid Leukemia. Cancer Res. 2024 Apr 1;84(7):1084-1100. doi: 10.1158/0008-5472.CAN-23-2659. PMID: 38266099.
Gose T, Aitken HM, Wang Y, Lynch J, Rampersaud E, Fukuda Y, Wills M, Baril SA, Ford RC, Shelat A, Mara MLO, Schuetz JD. The net electrostatic potential and hydration of ABCG2 affect substrate transport. Nat Commun. 2023 Aug 18;14(1):5035. doi: 10.1038/s41467-023-40610-5. PMID: 37596258; PMCID: PMC10439158.
Ranjit S, Wang Y, Zhu J, Cheepala SB, Schuetz EG, Cho WJ, Xu B, Robinson CG, Wu G, Naren AP, Schuetz JD. ABCC4 impacts megakaryopoiesis and protects megakaryocytes against 6-mercaptopurine induced cytotoxicity. Drug Resist Updat. 2024 Jan;72:101017. doi: 10.1016/j.drup.2023.101017. Epub 2023 Nov 8. PMID: 37988981; PMCID: PMC10874622.
Lynch J, Wang Y, Kanisha Kavdia YL, Fukuda Y, Ranjit S, Robinson CG, Grace CR, Xia Y, Peng J, Schuetz JD. PPIX-binding Proteins Reveal Porphyrin Synthesis and Ferroptosis Link. Communications Biology. June 24;Article number 673, 2023.
Wijaya J, Vo BT, Liu J, Xu B, Wu G, Wang Y, Peng J, Zhang J, Janke LJ, Orr BA, Yu J, Roussel MF, Schuetz JD. An ABC Transporter Drives Medulloblastoma Pathogenesis by Regulating Sonic Hedgehog Signaling. Cancer Res. 2020 Apr 1;80(7):1524-1537. doi: 10.1158/0008-5472.CAN-19-2054. Epub 2020 Jan 16. PMID: 31948942; PMCID: PMC7416697.
Pitre A, Ge Y, Lin W, Wang Y, Fukuda Y, Temirov J, Phillips AH, Peters JL, Fan Y, Ma J, Nourse A, Sinha C, Lin H, Kriwacki R, Downing JR, Gruber TA, Centonze VE, Naren AP, Chen T, Schuetz JD. An unexpected protein interaction promotes drug resistance in leukemia. Nat Commun. 2017 Nov 16;8(1):1547. doi: 10.1038/s41467-017-01678-y. PMID: 29146910; PMCID: PMC5691054.
Last update: June 2024