St. Jude Research

Research

Learn about published research as well as leading-edge basic and translational research initiatives from St. Jude laboratories.

Changing the trajectory of flu for the sickest patients
Changing the trajectory of flu for the sickest patients

Changing the trajectory of flu for the sickest patients

 David Boyd, PhD

Research reveals that supportive tissue in the lungs helps coordinate the immune response to flu by regulating access to the tissue and inflammation in the lungs.

It is better to be safe than fast when it comes to the development of a COVID-19 vaccine.
It is better to be safe than fast when it comes to the development of a COVID-19 vaccine.

COVID-19 vaccine development: better safe than fast

 Stacey Schultz-Cherry, PhD

This is the most important thing to remember about vaccines for COVID-19 and other diseases going through clinical trials.

Can common nasal bacteria be targeted to slow flu transmission? Maybe.
Can common nasal bacteria be targeted to slow flu transmission? Maybe.

Can common nasal bacteria be targeted to slow flu transmission? Maybe.

 Mary Powers

This new study shows that flu transmission and infection could be slowed or prevented by this simple technique.

T-Cell therapy may bridge treatment gap for pediatric acute myeloid leukemia
T-Cell therapy may bridge treatment gap for pediatric acute myeloid leukemia

T-Cell therapy may bridge treatment gap for pediatric acute myeloid leukemia

 Paulina Velasquez, MD

This clinical trial may be the key for leukemia patients getting a curative bone marrow transplant.

SMARCB1: Genetic ‘canary in a coal mine’ sparks research
SMARCB1: Genetic ‘canary in a coal mine’ sparks research

SMARCB1: Genetic ‘canary in a coal mine’ sparks research

 Erin Podolak, MA

Scientist spent more than a decade finding out how this genetic mutation causes different cancers.

Childhood Solid Tumor Network moves to the cloud with additional data and analytic tools
Childhood Solid Tumor Network moves to the cloud with additional data and analytic tools

Childhood Solid Tumor Network moves to the cloud with additional data and analytic tools

 Mary Powers

Scientists interested in studying pediatric solid tumors now have this comprehensive, interactive online shop for patient-derived tumor information.

Unraveling the ambiguity of risk for childhood cancer survivors
Unraveling the ambiguity of risk for childhood cancer survivors

Unraveling the ambiguity of risk for childhood cancer survivors

 Erin Podolak, MA

Clinical specialists are learning this about the future for childhood cancer survivors and how to help them.

Staff scientists in core research facilities accelerate and broaden biomedical discovery
Staff scientists in core research facilities accelerate and broaden biomedical discovery

Staff scientists in core research facilities accelerate and broaden biomedical discovery

 Gary Bridgman

These labs are highly specialized and deliver researchers access to advanced and speedy scientific results.

CHANGE-seq: a novel, simple and scalable method to understand genome editors
CHANGE-seq: a novel, simple and scalable method to understand genome editors

CHANGE-seq: a novel, simple and scalable method to understand genome editors

 Shengdar Tsai, PhD

Making DNA into a circle, called molecular circularization, has revealed a whole new way to look at genome editing.

Searching for the next pandemic flu virus? There’s another factor to keep in mind.
Searching for the next pandemic flu virus? There’s another factor to keep in mind.

Searching for the next pandemic flu virus? There’s another factor to keep in mind.

 Mary Powers

Researchers find the stability of this protein is key to the pandemic potential of swine flu.