Selected Publications
Chen S, Chang Y, Liangping Li, Acosta D, Yang L, Guo Q, Wang C, Turkes E, Morrison C, Julian D, Hester ME, Schnarre DW, Santiskulvong C, Song XS, Plummer JT, Serrano GE, Beach TG, Duff KE, Ma Q, Fu H. Spatially resolved transcriptomics reveals genes associated with the vulnerability of middle temporal gyrus in Alzheimer’s disease. Acta Pathologica Communications Dec 21, 2022. https://doi.org/10.1186/s40478-022-01494-6
Bhat S, Shibata T, Leong M, Plummer J, Vail E, Khan Z. Comparative upper respiratory tract transcriptomic profiling reveals a potential role of early activation of interferon pathway in severe COVID-19. Viruses Oct 1;14(10):2182, 2022. doi: 10.3390/v14102182
DeVries AA, Dennis J, Tyrer JP, Peng PC, Coetzee SG, Reyes AL, Plummer JT, Davis BD, Chen SC, Dezem FS, Ovarian Cancer Association Consortium, Freedman ML, Lawrenson KL, Pharoah PDP, Easton DF, Gayther SA, Jones MR. Copy Number Variants Associated with Epithelial Ovarian Cancer Risk in the Population. Journal of the National Cancer Institute Nov 14;114(11):1533-1544, 2022. doi: 10.1093/jnci/djac160
Blair AB, Wang J, Baker A, Li K, Niu N, Wang J, Shao Y, Funes VIP, Davelaar J, Dezem F, Plummer JT, Gong J, Hendifar A, Pandol S, Burkhart R, Zheng L, Osipov A. Dual stromal targeting sensitizes pancreatic adenocarcinoma for anti-PD-1 therapy. Gasteroenterology Nov;163(5):1267-1280.e7, 2022. doi: 10.1053/j.gastro.2022.06.027
Plummer JT†, Contreras D, Zheng W, Binek A, Zhang R, Dezem F, Davis BD, Chen SS, Sinuir-Martinez J, Stotland A, Kreimer S, Makhoul E, Heneidi S, Eno C, Shin B, Berg AH, Cheng S, Jordan S, Vail E, Van Eyk J, Morgan MA. USA SARS-CoV-2 Epsilon Variant: Though Highly Transmissible has an Adjusted Muted Host T-Cell Response. Clinical Infectious Diseases Nov 30;75(11):1940-1949, 2022. doi: 10.1093/cid/ciac295 †corresponding author
Svendsen CN, Yucer N, Ahdoot R, Workman MJ, Laperle AH, Recouvreux MS, Kurowski KJ, Naboulsi D, Liang V, Qu Y, Plummer JT, Gayther SA, Orsulic S, Karlan BY. Human iPSC-Derived Fallopian Tube Organoids Recapitulate BRCA1 Ovarian Cancer Initiation and Progression. Cell Reports Dec 28;37(13):110146, 2021. doi: 10.1016/j.celrep.2021.110146
Jordan S, Shin BH, Milfordgadsden TA, Chu M, Petrosyan A, Le C, Zabner R, Oft J, Pedraza I, Ammerman N, Cheng Susan, Vo A, Plummer JT, Berg A, Ge S, Toyoda M, Zhang R. T-cell Immunity Against COVID-19 and UK Variant in Infected and Vaccinated Individuals. Cellular and Molecular Immunity Nov;18(11):2554-2556, 2021. doi: 10.1038/s41423-021-00767-9
Kar S, Considine D, Tyrer J, Plummer JT, Chen S, Dezem F, Barbeira, A, Rajagopal, S, Rosenow S, Ovarian Cancer Association Consortium, Breast Cancer Assocation Consortium, Doherty J, Berchuck A, Lawrenson KL, Im HK, Manichaikul AW, Pharoah PDP, Gayther SA, Schildkraut J. Pleiotropy-guided transcriptome imputation from normal and tumor tissues identifies 80 new candidate breast and ovarian cancer susceptibility genes. Cancer Research Jul 8;2(3):100042, 2021. doi: 10.1016/j.xhgg.2021.100042.
Torabi-Dalivandan S, Plummer JT, Gayther SA. Risks and Function of Breast Cancer Susceptibility Alleles. Cancers Aug 5;13(16):3953, 2021. doi: 10.3390/cancers13163953
Halidpur P, Bernardo S, Aldinger K, Sivakumar T, Milman J, Sjoboen A, Dang D, Dubocanin D, Deng M, Timms AE, Davis BD, Plummer JT, Mankad K, Oztekin O, Manganaro L, Guimiot F, Adle-Biasette HA, Russo R, Siebert JR, Kidron D, Petrelli G, Roux N, Razavi F, Glass IA, Di Gioia C, Silvestri E, Millen KJ. Evidence of disrupted rhombic lip development in the pathogenesis of Dandy-Walker malformation. Acta Pathologica Oct;142(4):761-776, 2021. doi: 10.1007/s00401-021-02355-7.
Gouin III KH, Ing N, Plummer JT, Rosser CJ, Cheikh B, Oh C, Chen SS, Chan KS, Furuya H, Tourtelotte WG, Knott SRV, Theodorescu D. A neural type Cadherin 2 expressing epithelial cell subpopulation predicts response to surgery, chemotherapy and immunotherapy in bladder cancer. Nature Communications Aug 12;12(1):4906, 2021. doi: 10.1038/s41467-021-25103-7
Zhang WJ, Davis BD, Chen SS, Plummer JT†, Vail E. Emergence of a Novel SARS-CoV-2 Variant in Southern California. JAMA Apr 6;325(13):1324-1326, 2021. doi: 10.1001/jama.2021.1612. †corresponding author *Editorial by Dr. Anthony Fauci
Zhang, WJ, Govindavari, JP, Davis, BD, Chen, SS, Kim, JT, Song, JB, Lopetagui, J, Plummer, JT†, Vail, E. Analysis of SARS-CoV-2 Genomes from Southern California Reveals Community Transmission Pathways in the Early Stage of the US COVID-19 Pandemic JAMA Netw Open Oct 1;3(10):e2024191, 2020. doi: 10.1001/jamanetworkopen.2020.24191.24191 † corresponding author
Jones MR, Peng PC, Coetzee S, Tyrer J, Reyes AL, Corona de la Fuente R, Davis B, Chen S, Dezem F, Seo, JH. Ovarian Cancer Association Consortium, Berman BP, Freedman ML, Plummer JT, Lawrenson K, Pharoah P, Hazelett D, Gayther SA. Ovarian Cancer Risk Variants are Enriched in Histotype-Specific Enhancers that Disrupt Transcription Factor Binding Sites. AJHG Oct 1;107(4):622-635, 2020. doi: 10.1016/j.ajhg.2020.08.021
Sharma A, Garcia Jr G, Wang Y, Plummer JT, Morizono K, Arumugaswami V, Svendsen CN. Human iPSC-Derived Cardiomyocytes are Susceptible to SARS-CoV-2 Infection. Cell Reports Medicine Jul 21;1(4):100052, 2020. doi: 10.1016/j.xcrm.2020.100052
Pan J*, Silva TC*, Gull N*, Yang Q*, Plummer JT*, Chen S, Daigo K, Hamakubo T, Gery S, Ding LW, Jiang YY, Hu SY, Xu LY, Li EM, Ding Y, Klempner SJ, Berman BP, Koeffler HP, Lin DC. Lineage-Specific Epigenomic and Genomic Activation of the Oncogene HNF4A Promotes Gastrointestinal Adenocarcinomas. Cancer Research Jul 1;80(13):2722-2736, 2020. doi: 10.1158/0008-5472.CAN-20-0390.*shared co-first authors
Reyes ALP, Silva TC, Coetzee SG, Plummer JT, Davis B, Chen S, Hazelett D, Lawrenson K, Berman BP, Gayther SA, Jones MR. GENAVi: a Shiny web application for Gene Expression Normalization And Visualization. BMC Genomics Oct 16;20(1):745, 2019. doi: 10.1186/s12864-019-6073-7.
Chen L*, Huang M*, Plummer JT*, Pan J, Jiang YY, Silva TC, Gull N, Chen S, Ding LW, An O, Yang H, Cheng Y, Said JW, Doan W, Dinjens NM, Waters K, Tuli R, Gayther SA, Kempner SJ, Meltzer SJ, BermaN BP, Lin DC, Koeffler HP. Master transcription factors form interconnected circuitry and orchestrate transcriptional networks in esophageal adenocarcinoma. Gut Apr;69(4):630-640, 2019. doi: 10.1136/gutjnl-2019-318325 *shared co-first authors
Plummer JT, Gordon AJ, Levitt P. The Genetic Intersection of Neurodevelopmental Disorders and Shared Medical Comorbidities- Relations that Translate from Bench to Bedside. Frontiers in Psychiatry Aug 22;7:142, 2016. doi: 10.3389/fpsyt.2016.00142
Plummer JT, Evgrafov OV, Bergman MY, Friez M, Haiman CA, Levitt P, Aldinger KA. Transcriptional regulation of the MET receptor tyrosine kinase gene by MeCP2 and sex-specific expression in autism and Rett syndrome. Translational Psychiatry Oct 22;3(10):e316, 2013. doi: 10.1038/tp.2013.91
Aldinger KA*, Plummer JT*, Qiu SF, Levitt P. Genetics of Autism. Neuron Oct 20;72(2):418-8.e1, 2011. doi: 10.1016/j.neuron.2011.10.007 *shared co-first authors
Last update: March 2023