Education
MD, PhD - Washington University School of Medicine, St. Louis, MO
Honor & Awards
- 2011 and 2017 National President’s Award, Cooley’s Anemia Foundation
- 2010 Egan Family Foundation Chair in Transitional Medicine, Harvard Medical School
- 2009 A. Clifford Barger Excellence in Mentoring Award, Harvard Medical School
- 2008 Holcombe E. Grier Award for Excellence in Teaching, Children’s Hospital Boston & Dana Farber Cancer Institute
Research Interests
- Patient-oriented studies in nonmalignant hematology
Clinical Interests
- Non-malignant hematology, including ITP, thalassemia, transfusional iron overload, hemophilia and thrombosis
Selected Publications
Neufeld EJ. Which pediatric ITP patients will go on to lupus? Blood Apr 18;143(16):1553-1554, 2024.
Liesner RJ, Abraham A, Altisent C, Belletrutti MJ, Carcao M, Carvalho M, Chambost H, Chan AKC, Dubey L, Ducore J, Gattens M, Gresele P, Gruel Y, Guillet B, Jimenez-Yuste V, Kitanovski L, Klukowska A, Lohade S, Mancuso ME, Oldenburg J, Pavlova A, Pollio B, Sigaud M, Vdovin V, Vilchevska K, Wu JKM, Jansen M, Belyanskaya L, Walter O, Knaub S, Neufeld EJ. Simoctocog alfa (Nuwiq) in previously untreated patients with severe haemophilia A: Final results of the NuProtect study. Thromb Haemost Feb 13, 2021. doi: 10.1055/s-0040-1722623. Online ahead of print.
Croteau SE, Cheng D, Cohen AJ, Holmes CE, Malec LM, Silvey M, Thornburg CD, Wheeler AP, Kouides PA, Raffini LJ, Neufeld EJ. Regional variation and cost implications of prescribed extended half-life factor concentrates among U.S. Haemophilia Treatment Centres for patients with moderate and severe haemophilia. Haemophilia Jul;25(4):668-675, 2019. doi: 10.1111/hae.13758. Epub Apr 17, 2019.
Neufeld EJ, Negrier C, Benchikh El, Fegoun S, Cooper DL, Rojas-Rios A, Seremetis S. Recombinant activated factor VII in approved indications: Update on safety. Haemophilia July 2018.
Iorio A, Blanchette V, Blatny J, Collins P, Fischer K, Neufeld E. Estimating and interpreting the pharmacokinetic profiles of individual patients with hemophilia A or B using a population pharmacokinetic approach: Communication from the SSC of the ISTH. J Thromb Haemost 15(12):2461-2465, 2017.
Schoettler ML, Graham D, Tao W, Stack M, Shu E, Kerr L, Neufeld EJ, Grace RF. Increasing observation rates in low-risk pediatric immune thrombocytopenia using a standardized clinical assessment and management plan (SCAMP®). Pediatr Blood Cancer May; 64(5), 2017. doi: 10.1002/pbc.26303. Epub 2016 Oct 26. PMID: 27781392; PMCID: PPMC5366076
Cattivelli K, Campagna DR, Schmitz-Abe K, Heeney MM, Yaish HM, Caruso Brown AE, Kearney S, Walkovich K, Markianos K, Fleming MD, Neufeld EJ. Ringed sideroblasts in β-thalassemia. Pediatr Blood Cancer May;64(5), 2017. doi: 10.1002/pbc.26324. Epub 2016 Nov 3. PMID: 27808451
Srivastava A, Serban M, Werner S, Schwartz BA, Kessler CM; Wonders Study Investigators. Efficacy and safety of a VWF/FVIII concentrate (Wilate®) in inherited von Willebrand disease patients undergoing surgical procedures. Haemophilia Mar;23(2):264-272, 2017. doi: 10.1111/hae.13106. Epub 2016 Dec 27. PMID: 28026130
Croteau, SE, Abajas YL, Wolberg AS, Nielsen BI, Marx GR, Baird CW, Neufeld EJ, Monahan PE. Recombinant porcine factor VIII for high-risk surgery in paediatric congenital haemophilia A with high-titre inhibitor. Haemophilia Mar;23(2):e93-e98, 2017. doi: 10.1111/hae.13157. Epub 2017 Jan 25. PMID: 28124406; PMCID: PMC5354962
Iorio A, Keepanasseril A, Foster G, Navarro-Ruan T, McEneny-King A, Edginton AN, Thabane L; WAPPS-Hemo co-investigator network. Development of a Web-Accessible Population Pharmacokinetic Service-Hemophilia (WAPPS-Hemo): Study Protocol. JMIR Res Protoc Dec 15;5(4):e239, 2016. PMID: 27977390; PMCID: PMC5200844
Nandivada P, Anez-Bustillos L, O'Loughlin AA, Mitchell PD, Baker MA, Dao DT, Fell GL, Potemkin AK, Gura KM, Neufeld EJ, Puder M. Risk of post-procedural bleeding in children on intravenous fish oil. Am J Surg Dec 1. pii: S0002-9610(16)30462-7, 2016. doi: 10.1016/j.amjsurg.2016.10.026. Epub ahead of print. PMID: 27979360
Recht M, Konkle BA, Jackson S, Neufeld EJ, Rockwood K, Pipe S. Recognizing the need for personalization of haemophilia patient-reported outcomes in the prophylaxis era. Haemophilia Nov;22(6):825-832, 2016. doi: 10.1111/hae.13066. Epub 2016 Aug 31. Review. PMID: 27581872
Croteau SE, Nakar C, Neufeld EJ, Shapiro A, Cooper DL. Safety and efficacy of recombinant factor VIIa by pediatric age cohort: reassessment of compassionate use and trial data supporting US label. Pediatr Blood Cancer Oct;63(10):1822-8, 2016. doi: 10.1002/pbc.26082. Epub 2016 May 27. PMID: 27232114
Platt CD, D'Angelo L, Neufeld EJ, Broyles AD. Skin testing, graded challenge, and desensitization to von Willebrand factor (VWF) products in type III von Willebrand disease (VWD). J Allergy Clin Immunol Pract Sep-Oct;4(5):1006-8, 2016. doi: 10.1016/j.jaip.2016.05.017. Epub 2016 Jul 9. PMID: 27406969
Neunert C, Despotovic J, Haley K, Lambert MP, Nottage K, Shimano K, Bennett C, Klaassen R, Stine K, Thompson A, Pastore Y, Brown T, Forbes PW, Grace RF; Pediatric ITP Consortium of North America (ICON). Thrombopoietin Receptor Agonist Use in Children: Data From the Pediatric ITP Consortium of North America ICON2 Study. Pediatr Blood Cancer Aug;63(8):1407-13, 2016. doi: 10.1002/pbc.26003. Epub 2016 May 2. PMID: 27135461
Croteau, SE, Padula M, Quint K, D'Angelo L, Neufeld EJ. Center-Based Quality Initiative Targets Youth Preparedness for Medical Independence: HEMO-Milestones Tool in a Comprehensive Hemophilia Clinic Setting. Pediatr Blood Cancer Mar;63(3):499-503, 2016. doi: 10.1002/pbc.25807. Epub 2015 Oct 23. PMID: 26496140
Mehta DA, Oladapo AO, Epstein JD, Novack AR, Neufeld EJ, Hay JW. A Budget Impact Model of Hemophilia Bypassing Agent Prophylaxis Relative to Recombinant Factor VIIa On-Demand. J Manag Care Spec Pharm Feb;22(2):149-57, 2016. doi: 10.18553/jmcp.2016.22.2.149. PMID: 27015254
Sobota, AE, Umeh E, Mack JW. Young Adult Perspectives on a Successful Transition from Pediatric to Adult Care in Sickle Cell Disease. J Hematol Res 2015 Dec;2(1):17-24, 2015. PMID: 27175364; PMCID: PMC4862600
Kumar M, Lambert MP, Breakey V, Buchanan GR, Neier M, Neufeld EJ, Kempert P, Neunert CE, Nottage K, Klaassen RJ; ITP Consortium of North America.. Sports Participation in Children and Adolescents with Immune Thrombocytopenia (ITP). Pediatr Blood Cancer Dec;62(12):2223-5, 2015. doi: 10.1002/pbc.25644. Epub 2015 Jul 14. PMID: 26174203
Grace RF, Zanella A, Neufeld EJ, Morton, DH, Eber, S, Yaish H, and Glader B. Erythrocyte Pyruvate Kinase Deficiency: 2015 Status Report. Am J Hematol September 09, 2015. PMID: 26087744
Morris CR, Kim HY, Klings ES, Wood J, Porter JB, Trachtenberg F, Sweeters N, Olivieri NF, Kwiatkowski JL, Virzi L, Hassell K, Taher A, Neufeld EJ, et, al. Dysregulated arginine metabolism and cardiopulmonary dysfunction in patients with thalassaemia. Blood Apr. 24, 2015. Epub ahead of print. PMID: 25907665
Croteau SE, Saxena K, Neufeld EJ. Correlation between dispensed and prescribed doses of factor products for bleeding disorders: can a small, centre-based pharmacy hit the mark? Haemophilia Mar 21, 2015. PMID: 25311503
Wood JC, Zhang P, Rienhoff H, Abi-Saab W, Neufeld EJ. Liver MRI is more precise than liver biopsy for assessing total body iron balance: A comparison of MRI relaxometry with simulated liver biopsy results. Magn Reson Imaging July, 2015. PMID: 25708262
Obeng EA, Harney KM, Moniz T, Arnold A, Neufeld EJ, Trenor CC 3rd. Pediatric Heparin-Induced Thrombocytopenia: Prevalence, Thrombotic Risk, and Application of the 4Ts Scoring System. J Pediatr Oct 14;S0022-3476(14)00845-2, 2014. PMID: 25444534
Recht M, Neufeld EJ, Sharma VR, Solem CT, Pickard AS, Gut RZ, Cooper DL. Impact of Acute Bleeding on Daily Activities of Patients with Congenital Hemophilia with Inhibitors and Their Caregivers and Families: Observations from the Dosing Observational Study in Hemophilia (DOSE). Value Health Sep;17(6):744-8, 2014. PMID: 25236999
Leissinger C, Josephson CD, Granger S, Konkle BA, Kruse-Jarres R, Ragni MV, Journeycake JM, Valentino L, Key NS, Gill JC, McCrae KR, Neufeld EJ, Manno C, Raffini L, Saxena K, Torres M, Marder V, Bennett CM, Assmann SF. Rituximab for treatment of inhibitors in haemophilia A. A Phase II Study. Thromb Haemost Sep 2;112(3):445-58, 2014. PMID: 24919980
Morrison JF, Neufeld EJ, Grace RF. The use of erythropoietin-stimulating agents versus supportive care in newborns with hereditary spherocytosis: a single centre's experience. Eur J Haematol Aug; 93(2):161-4, 2014. PMID: 24660843
Nichols-Vinueza DX, White MT, Powell AJ, Banka P, Neufeld EJ. MRI guided iron assessment and oral chelator use improve iron status in thalassemia major patients. Am J Hematol Jul;89(7):684-8, 2014. PMID: 24652616
Trachtenberg FL, Gerstenberger E, Xu Y, Mednick L, Sobota A, Ware H, Thompson AA, Neufeld EJ, Yamashita R. Relationship among chelator adherence, change in chelators, and quality of life in Thalassemia. Qual Life Res Oct;23(8):2277-88, 2014. PMID: 24682717
Wood JC, Zhang P, Rienhoff H, Abi-Saab W, Neufeld E. R2 and R2* are equally effective in evaluating chronic response to iron chelation. Am J Hematol May;89(5):505-8, 2014. PMID: 24452753
Klaassen RJ, Barrowman N, Merelles-Pulcini M, Vichinsky EP, Sweeters N, Kirby-Allen M, Neufeld EJ, Kwiatkowski JL, Wu J, Vickars L, Blanchette VS, Forgie M, Yamashita R, Wong-Rieger D, Young NL. Validation and reliability of a disease-specific quality of life measure (the TranQol) in adults and children with thalassaemia major. Br J Haematol Feb;164(3):431-7, 2014. PMID: 24180641
Shapiro AD, Neufeld EJ, Blanchette V, Salaj P, Gut R, Cooper, D. Safety of recombinant activated factor VII (rFVIIa) in patients with congenital hemophilia with inhibitors: overall rFVIIa exposure and intervals following high (>240 mcg/kg) rFVIIa doses across clinical trials and registries. Haemophilia Jan;20(1):e23-31, 2014. PMID: 24354484.
Vichinsky E, Neumayr L, Trimble S, Giardina PJ, Cohen AR, Coates T, Boudreaux J, Neufeld EJ, Kenney K, Grant A, Thompson AA; CDC Thalassemia Investigators. Transfusion complications in thalassemia patients: a report from T Centers for Disease Control and Prevention. Transfusion Apr;54(4):972-81, 2014. PMID: 23889533
Last update: August 2024