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Spotiphy integrative analysis tool turns spatial RNA sequencing into imager
03/12/2025
Explore Spotiphy, a program that enhances spatial transcriptomics, providing single-cell resolution & comprehensive gene coverage with a generative algorithm.
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Repurposed ALS drug becomes imaging probe to help diagnose neurodegeneration
03/05/2025
See how scientists at St. Jude Children’s Research Hospital use positron emission tomography scanning and an ALS drug edaravone to detect neurodegeneration
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St. Jude scientists solve mystery of how the drug retinoic acid works to treat neuroblastoma
02/28/2025
Find new research showing how retinoic acid hijacks a developmental pathway in metastasized neuroblastoma in the bone marrow, solving a 50 year-long mystery.
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Altering tumor microenvironment may reduce relapses after leukemia immunotherapy
02/25/2025
Discover research identifying GRP65 as a potential biomarker predicting relapse after immunotherapy in childhood leukemia & potential combination therapies.
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Promising results from first prenatal therapy for spinal muscular atrophy
02/19/2025
See how spinal muscular atrophy (SMA) can be treated prenatally in utero with the survival of motor neuron 2-directed RNA splicing modifier risdiplam (Evrysdi)
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2025 Damon Runyon- St. Jude Fellows announced
02/13/2025
Cancer researchers in Seattle, San Francisco, Boston, New York and Memphis were selected as Pediatric Fellows
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WHO, St. Jude launch groundbreaking international delivery of childhood cancer medicines
02/11/2025
St. Jude Global announces delivery of critically-needed cancer medicines to countries
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St. Jude researchers create tool incorporating transcriptome size to improve RNA-seq analysis
02/03/2025
Discover how ReDeconv accounts for transcriptome size to get more from bulk & single-cell RNA sequencing analysis with better deconvolution and normalization.
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Schwarz wins presidential science award
01/30/2025
The Presidential Early Career Award for Scientists and Engineers (PECASE) recognizes innovative and far-reaching developments in science
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Elizabeth Hillman joins St. Jude as chair of Imaging Sciences
01/22/2025
Hillman joins St. Jude from Columbia University to bring technology innovators and accelerate scientific discovery and advance clinical care.
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Brenda J. Weigel, MD, named vice president of clinical research industry engagement at St. Jude Children's Research Hospital
01/21/2025
Brenda Weigel MD, pediatric tumor expert, will advance external partnerships to enhance clinical research for children with catastrophic diseases.
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ZIC1 gene drives distinct medulloblastoma types in different ways
01/08/2025
Discover research showing how the context of distinct & opposing mutations in the ZIC1 gene drive Group 4 (G4) and sonic hedgehog (SHH) medulloblastoma types.
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St. Jude scientists create scalable solution for analyzing single-cell data
01/08/2025
Explore how Consensus and Scalable Inference of Gene Expression Programs (CSI-GEP)’s unsupervised machine learning provides unbiased single-cell RNA analysis.
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Signaling circuit interplay pushes newborn neurons out of the neuronal nest
01/07/2025
See how Netrin-1, Siah2, Pard3 and JamC interconnect in a coincidence detection circuit in neuronal development and migration from germinal zone
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Discovery of ‘pliancy genes’ showcases role of latent epigenetic programs in retinal recovery
01/02/2025
Learn how the discovery of pliancy genes by scientists at St. Jude showcases the role of latent epigenetic programs in the retina’s response to stress.
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Mitochondrial DNA plays an underappreciated role in leukemia development
01/01/2025
See how mitochondrial DNA (mtDNA) mutation affects leukemogenesis by altering metabolic pathways via pyruvate dehydrogenase and affecting cell plasticity
