Selected Publications
(*Co-first author, #Corresponding author, and Trainee)
Zahr RS, Kang G, Zhang X, Rashkin SR, Kovesdy CP, Takemoto C, Weiss M, Lebensburger J, Ataga KI, Saraf SL. Development of Polygenic Risk Score for Persistent Albuminuria in Children and Adults with Sickle Cell Anemia. American Journal of Hematology, 2025 (in press). (PMID: 40186439)
Smith BD, Hankins JS, Kang G, Takemoto C, Rai P, Chen P-L, King BA, Hoehn ME. Investigation of Sickle Cell Retinopathy in Pediatric and Adolescent Patients Enrolled in a Large Cohort Study. Ophthalmology, 2025 Apr 4:S0161-6420(25)00216-7, 2025. (PMID: 40188852)
Liyanage JSS, Hankins JS, Estepp JH, Srivastava D, Rashkin SR, Takemoto C, Li Y, Cui Y, Mori M, Weiss MJ, Kang G#. A Novel One-Sample Mendelian Randomization Approach for Count-Type Outcomes That Is Robust to Correlated and Uncorrelated Pleiotropic Effects. Genetic Epidemiology, 49(1):e22602 2025. (PMID: 39498871)
Khan H, Porter JS, Ding J, Wang WC, Gurney JG, Kang G, Davis R, Hodges JR, Hankins JS. Social Determinants of Health Are Associated with Poor Health Outcomes Among Preschool Children with Sickle Cell Disease. Blood Advances (In press), 2025. (PMID: 39373640)
Ojewunmi OO, Adeyemo T, Oyetunji AI, Inyang B, Akinrodoye A, Mkumbe BS, Gardener K, Rooks H, Brewin J, Patel H, Lee S-H, Chung, R, Rashkin S, Kang G, Chianumba R, Sangeda R, Mwita L, Isa H, Agumadu U-N, Ekong R, Faruk JA, Jamoh BY, Adebiyi NM, Umar IA, Hassan A, Grace C, Goel A, Inusa B, Faflchi M, Nkya S, Makani J, Ahmad H, Nnodu OE, Strouboulis J, Menzel S. The genetic dissection of fetal haemoglobin persistence in sickle cell disease in Nigeria. Human Molecular Genetics, 2024. (PMID: 38339995)
Alberts NM, Gilbert A, Kang G, Okhomina VI, Flynn JS, Hodges J, Hankins J, Klosky J. Agreement between youth and caregiver report of pain and functioning in pediatric sickle cell disease: PedsQLTM Sickle Cell Disease Module. Pain, 165(3): 715-722, 2024. (PMID: 37878652)
Mayuranathan T, Newby GA, Feng R, Yao Y, Mayberry K, Kang G, Lazzarotto CR, Li Y, Levine RM, Dempsey EA, Porter SN, Doerfler PA, Zhang J, Jang Y, Bhoopalan SV, Sharma A, Tisdale JF, Pruett-Miller SM, Cheng Y, Tsai SQ, Liu DR, Weiss MJ, Yen JS. Potent and uniform fetal hemoglobin induction via base editing. Nature Genetics 55(7):1210-122, 2023. (PMID: 37400614)
Zhao Y, Zhang H, Wang T, Kang G. System identification under saturated precise or set-valued measurements. Science in China: Information Sciences 66: 112204:1-20, 2023.
Melo-Cardenas J, Bezavada L, Crawford JC, Gurbuxani S, Cotton A, Kang G, Gossett J, Marinaccio C, Weinberg R, Hoffman R, Migliaccio AR, Zheng Y, Derecka M, Rinaldi C, Crispino J. IL-13/IL-4 signaling contributes to fibrotic progression of the myeloproliferative neoplasms. Blood 140(26): 2805-2817, 2022. (PMID: 36283106)
MLiyanage JSS*, Estepp J*, Srivastava K, Raskin S, Sheehan VA, Hankins J, Takemoto C, Li Y, Cui Y, Mori T, Burgess S, DeBaun M, Kang G#. A versatile and efficeint novel approach for Mendelian randomization analysis with application to assess the causal effect of fetal hemoglobin on anemia in sickle cell anemia. Mathematics 10(20), 3743, 2022.
Ganuza M, Hall T, Myers J, Nevitt C, Sánchez-Lanzas R, Chabot A, Ding J, Kooienga E, Caprio C, Finkelstein D, Kang G, Obeng E, McKinney-Freeman S. Murine foetal liver supports limited detectable expansion of life-long hematopoietic progenitors. Nature Cell Biology 24(10): 1475-1486, 2022. (PMID: 36202972)
Liyanage JSS, Estepp J, Srivastava K, Li Y, Mori T, Kang G#. GMEPS: a fast and efficient likelihood approach for genome-wide mediation analysis under extreme phenotype sequenicng. Statistical Applications in Genetics and Molecuar Biology 21(1), 2022. (PMID: 35266368)
Rampersaud E*, Kang G*, Estepp J, Palmer L, Hankins J, Bi W, Sheehan V, Boulos N, Chang TC, Chen W, Cheng Y, Downing JR, Easton J, Hodges J, Mulder H, Rusch M, Sapkota Y, Sharma A, Sumazin P, Tang X, Thrasher A, Villavicencio M, Wang S, Wang WC, Yasui Y, DeBaun M, Zhang J, Wu G, Weiss MJ. A Polygenic Score for Acute Vaso-Occlusive Pain in Pediatric Sickle Cell Disease. Blood Advances 5(14): 2839-2851, 2021. (PMID: 34283174)
Mamcarz E, Zhou S, Lockey T, Abdelsamed H, Cross S, Kang G, Ma Z, Dowdy J, Triplett B, Li C, Maron G, Aldave JC, Dokmeci E, Love JT, da Matta Ain AC, van der Watt H, Tang X, Janssen W, Ryu BY, Gottschalk S, De Ravin SS, Weiss MJ, Youngblood B, Long-Boyle JR, Meagher MM, Malech HL, Puck JM, Cowan MJ, Sorrentino BP. Lentiviral gene therapy with low dose busulfan for infants with X-SCID. The New England Journal of Medicine, 380(16): 1525-1534, 2019. (PMID: 30995372)
https://www.stjude.org/media-resources/news-releases/2019-medicine-science-news/st-jude-gene-therapy-cures-babies-with-bubble-boy-disease.html
Chen J*, Kang G*, VanderWeele T, Zhang C, Mukherjee B. Efficient designs of gene-environment interaction studies: implications of Hardy-Weinberg equilibrium and gene-environment independence. Statistics in Medicine 31(22):2516-2530, 2012. PMID: 22362617 PMCID: PMC3448495
Jiang B, Zhang X, Zuo Y, Kang G. A powerful truncated tail strength method for testing mltiple hypotheses in a dataset. J Theor Biol 277:67-73, 2011. PMID: 21295595 *The Science Unbound Foundation Best Paper Award in General Statistics Research. http://www.scienceunboundfoundation.org/2012.html
Kang G, Ye K, Allison DB, Liu N, Gao G. Weighted multiple hypothesis testing procedures. Stat Appl Genet Mol Biol 8(1):Article 23, 2009. PMID: 19409067 PMCID: PMC2703613
Kang G, Yue W, Zhang J, Cui Y, Zuo Y, Zhang D. An entropy-based approach for testing genetic epistasis underlying complex diseases. J Theor Biol 250:362-374, 2008. PMID: 17996908
Cui Y, Kang G, Sun K, Qian M, Romero R, Fu W. Gene-centric genome-wide association study via entropy. Genetics 179:637-650, 2008. PMCID: PMC2390640
*Research highlighted in Nature Review Genetics in 2008. http://www.nature.com/nrg/journal/v9/n6/full/nrg2387.html
Kang G, Yue W, Zhang J, Huebner M, Zhang H, Ruan Y, Lu T, Ling Y, Zuo Y, Zhang D. Two-stage designs to identify the effects of SNP combinations on complex diseases. Journal of Human Genetics 53:739-746, 2008. PMID: 18584117
*The Science Unbound Foundation Best Paper Award in Statistical Genetics Research. http://www.scienceunboundfoundation.org/2009.html
Kang G, Li S, Zhang J. Entropy-based models for interpreting life systems in traditional Chinese medicine. Evidence-based Complementary and Alternative Medicine 5(3):273-279, 2008. PMID: 18830452 PMCID: PMC2529388
*Reported by the international media of “International Adaptogens” (Venezuela); http://www.adaptogeno.com/svms/noticias/noticia367.asp
#Included in the monograph of “Transgénicos”(Cuba)
Last update: April 2025