Selected Publications
Turner AJ, Haidar CE, Yang W, Boone EC, Offer SM, Empey PE, Haddad A, Tahir S, Scharer G, Broeckel, Gaedigk A. Updated DPYD HapB3 haplotype structure and implications for pharmacogenomic testing. Clin Transl Sci Dec 21, 2023. doi:10.1111/cts.13699. [Epub ahead of print]. PubMed PMID: 38129972
Gammal RS, Pirmohamed M, Somogyi AA, Morris SA, Formea CM, Elchynski AL, Oshikoya KA, McLeod HL, Haidar CE, Whirl-Carrillo M, Klein TE, Caudle KE, Relling MV. Expanded Clinical Pharmacogenetics Implementation Consortium Guideline for Medication Use in the Context of G6PD Genotype. Clin Pharmacol Ther May;113(5):973-985, 2023. doi: 10.1002/cpt.2735. PMID: 36049896
Haidar CE, Petry N, Oxencis C, Douglas JS, Hoffman JM. ASHP Statement on the pharmacist's role in clinical pharmacogenomics. Am J Health Syst Pharm Apr 1;79(8):704-707, 2022. PMID:34487145.
Nguyen JQ, Crews KR, Moore BT, Kornegay NM, Baker DK, Hasan M, Campbell PK, Dean SM, Relling MV, Hoffman JM, Haidar CE. Clinician adherence to pharmacogenomics prescribing recommendations in clinical decision support alerts. J Am Med Inform Assoc Dec 13;30(1):132-138, 2022. PMCID: PMC9748527
Haidar CE, Crews KR, Hoffman JM, Relling MV, Caudle KE. Advancing Pharmacogenomics from single-gene to preemptive testing. Annu Rev Genomics Hum Genet Aug 31:23:449-473, 2022. doi: 10.1146/annurev-genom-111621-102737. PMID: 35537468
Morris SA, Crews KR, Hayden RT, Takemoto CM, Yang W, Baker DK, Broeckel U, Relling MV, Haidar CE. Incorporating G6PD genotyping to identify patient with G6PD deficiency. Pharmacogenet Genomics 32(3):87-93, 2022. PMID: 34693927
Turner AJ, Aggarwal P, Boone EC, Haidar CE, Relling MV, Derezinski AD, Broeckel U, Gaedigk A. Identification of CYP2D6 haplotypes that interfere with commonly used assays for copy number variation characterization. J Mol Diagn 23(5):577-88, 2021. PMCID PMC8176139
Crews KR, Monte AA, Huddart R, Caudle KE, Kharasch ED, Gaedigk A, Dunnenberger HM, Leeder JS, Callaghan JT, Samer CF, Klein TE, Haidar CE, Van Driest SL, Ruano G, Sangkuhl K, Cavallari LH, Müller DJ, Prows CA, Nagy M, Somogyi AA, Skaar TC. Clinical Pharmacogenetics Implementation Consortium Guideline for CYP2D6, OPRM1, and COMT genotypes and select opioid therapy. Clin Pharmacol Ther Oct;110(4):888-896., 2021. PMCID: PMC8249478
Howard Sharp KM, Jurbergs N, Ouma A, Harrison L, Gerhardt E, Taylor L, Hamilton K, McGee RB, Nuccio R, Quinn E, Hines-Dowell S, Kesserwan C, Sunkara A, Gattuso JS, Pritchard M, Mandrell B, Relling MV, Haidar CE, Kang G, Johnson LM, Nichols KE. Factors Associated with Declining to Participate in a Pediatric Oncology Next Generation Sequencing Study. JCO Precis Oncol 4:202-211, 2020. doi: 10.1200/PO.19.00213. .PMID: 32395682.
Caudle KE, Sangkuhl K, Whirl-Carrillo M, Swen JJ, Haidar CE, Klein TE, Gammal RS, Relling MV, Scott SA, Hertz DL, Guchelaar HJ, Gaedigk A. Standardizing CYP2D6 Genotype to Phenotype Translation: Consensus Recommendations from the Clinical Pharmacogenetics Implementation Consortium and Dutch Pharmacogenetics Working Group. Clin Transl Sci Jan;13(1):116-124, 2020. doi: 10.1111/cts.12692. PMID: 31647186.
Haidar CE, Relling MV, Hoffman JM. Preemptively Precise: Returning and Updating Pharmacogenetic Test Results to Realize the Benefits of Preemptive Testing. Clin Pharmacol Ther Nov;106(5):942-944, 2019. doi: 10.1002/cpt.1613. PMCID: PMC6777995.
Hoshitsuki K, Crews KR, Yang W, Smith CA, Hankins JS, Turner AJ, Broeckel U, McMillin GA, Relling MV, Haidar CE. Challenges in clinical implementation of CYP2D6 genotyping: choice of variants to test affects phenotype determination. Genet Med. Jan;22(1):232-233., 2020. doi: 10.1038/s41436-019-0614-y. PMID: 31341243.
Gammal RS, Caudle KE, Quinn CT, Wang WC, Gaedigk A, Prows CA, Haidar CE, Taylor AK, Klein TE, Sangkuhl K, Hankins JS, Crews KR. The Case for Pharmacogenetics-Guided Prescribing of Codeine in Children. Clin Pharmacol Ther Jun;105(6):1300-1302, 2019. doi: 10.1002/cpt.1260. PMID: 30467830.
Robinson KM, Yang W, Haidar CE, Hankins JS, Jay DW, Kornegay N, Rubnitz JE, Broeckel U, Cheng C, Pui CH, Jeha S, Relling MV. Concordance between glucose-6-phosphate dehydrogenase (G6PD) genotype and phenotype and rasburicase use in patients with hematologic malignancies. Pharmacogenomics J Jun;19(3):305-314, 2018. doi: 10.1038/s41397-018-0043-3. PMID: 30206300
Keeling NJ, Rosenthal MM, West-Strum D, Patel A, Haidar CE, Hoffman JM. Preemptive pharmacogenetic testing: Exploring the knowledge and perspectives of United States payers. Genetics in Medicine May;21(5):1224-1232, 2017. doi:10.1038/gim.2017.181
Haidar CE, Hoffman JM, Gammal RS, Relling MV, Crews KR. Development of a Post-Graduate Year 2 pharmacy residency in clinical pharmacogenetics. Am J Health Syst Pharm 74(6):409-15, 2017. PMC5499519
Luzum J, Pakyz R, Elsey A, Haidar C, Peterson J, Whirl-Carrillo M, Handelman S, Palmer K, Pulley J, Beller M, Schildcrout J, Field J, Weitzel K, Cooper-DeHoff R, Cavallari L, O'Donnell P, Altman R, Pereira N, Ratain M, Roden D, Embi P, Sadee W, Klein T, Johnson J, Relling M, Wang L, Weinshilboum R, Shuldiner A, Freimuth R. The Pharmacogenomics Research Network Translational Pharmacogenetics Program: Outcomes and metrics of pharmacogenetic implementations across diverse healthcare systems. Clin Pharmacol Ther 102(3):502-10, 2017. Epub 2017 Jun 9. PMCID: PMC5511786
Pasternak AL, Crew KR, Caudle KE, Smith C, Pei D, Cheng C, Broeckel U, Gaur AH, Hankins J, Relling MV, Haidar CE. The impact of the UGT1A1*60 allele on bilirubin serum concentrations. Pharmacogenomics 18(1)5-16, 2017. Epub 2016 Dec 14. PMID: 27967321
Hicks JK, Dunnenberger HM, Gumpper KF, Haidar CE, Hoffman JM. Integrating pharmacogenomics into electronic health records with clinical decision support. Am J Health Syst Pharm 73(23):1967-76, 2016. PMCID: PMC5117634
Yang W, Wu G, Broeckel U, Smith C, Turner V, Haidar CE, Wang S, Carter R, Karol S, Neale G, Crews K, Yang J, Mullighan C, Downing J, Evans W, Relling M. Comparison of Genome Sequencing and Clinical Genotyping for Pharmacogenes. Clin Pharmacol Ther 100(4):380-8, 2016. Epub 2016 Aug 18. PMCID: PMC5684873
Gammal RS, Crews KR, Haidar CE, Hoffman JM, Baker DK, Barker PJ; Estepp JH, Pei D, Broeckel U, Wang W, Weiss MJ, Relling MV, Hankins J. Leveraging Pharmacogenetics for Safe Codeine Use in Children - Emphasis on Sickle Cell Disease. Pediatrics 138(1):e20153479, 2016. doi: 10.1542/peds.2015-3479. PMCID: PMC4925073
Gammal RS, Court MH, Haidar CE, Iwuchukwu OF, Gaur AH, Alvarellos M, Guillemette C, Lennox JL, Whirl-Carrillo M, Brummel SS, Ratain MJ, Klein TE, Schackman BR, Caudle KE, Haas DW. Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for UGT1A1 and Atazanavir Prescribing. Clin Pharmacol Ther 99(4):363-9, 2016. Epub 2015 Nov 9. PMCID: PMC4785051
Gammal RS, Crews KR, Haidar CE, Hoffman JM, Baker DK, Barker PJ; Estepp JH, Pei D, Broeckel U, Wang W, Weiss MJ, Relling MV, Hankins J. Leveraging Pharmacogenetics for Safe Codeine Use in Children - Emphasis on Sickle Cell Disease. Pediatrics 138(1):e20153479, 2016. doi: 10.1542/peds.2015-3479. PMCID: PMC4925073
Yang W, Wu G, Broeckel U, Smith C, Turner V, Haidar CE, Wang S, Carter R, Karol S, Neale G, Crews K, Yang J, Mullighan C, Downing J, Evans W, Relling M. Comparison of Genome Sequencing and Clinical Genotyping for Pharmacogenes. Clin Pharmacol Ther 100(4):380-8, 2016. Epub 2016 Aug 18. PMCID: PMC5684873
Hicks JK, Dunnenberger HM, Gumpper KF, Haidar CE, Hoffman JM. Integrating pharmacogenomics into electronic health records with clinical decision support. Am J Health Syst Pharm 73(23):1967-76, 2016. PMCID:PMC5117634
Pasternak AL, Crew KR, Caudle KE, Smith C, Pei D, Cheng C, Broeckel U, Gaur AH, Hankins J, Relling MV, Haidar CE. The impact of the UGT1A1*60 allele on bilirubin serum concentrations. Pharmacogenomics 18(1)5-16, 2017. Epub 2016 Dec 14. PMID: 27967321.
Luzum J, Pakyz R, Elsey A, Haidar C, Peterson J, Whirl-Carrillo M, Handelman S, Palmer K, Pulley J, Beller M, Schildcrout J, Field J, Weitzel K, Cooper-DeHoff R, Cavallari L, O'Donnell P, Altman R, Pereira N, Ratain M, Roden D, Embi P, Sadee W, Klein T, Johnson J, Relling M, Wang L, Weinshilboum R, Shuldiner A, Freimuth R. The Pharmacogenomics Research Network Translational Pharmacogenetics Program: Outcomes and metrics of pharmacogenetic implementations across diverse healthcare systems. Clin Pharmacol Ther Sep;102(3):502-510, 2017. Jan 16. doi: 10.1002/cpt.630. [Epub ahead of print]. PMCID:PMC5511786
Haidar CE, Hoffman JM, Gammal RS, Relling MV, Crews KR. Development of a Post-Graduate Year 2 Pharmacy Residency in Clinical Pharmacogenetics. Am J Health Syst Pharm. Am J Health Syst Pharm 74(6):409-15, 2017. PMCID:PMC5499519
Hicks JK, Crews KR, Flynn P, Haidar CE, Daniels CC, Yang W, Panetta JC, Pei D, Scott JR, Molinelli A, Broeckel U, Bhojwani D, Evans WE, Relling MV. Voriconazole plasma concentrations in immunocompromised pediatric patients vary by CYP2C19 diplotypes. Pharmacogenomics 15(8):1065-1078, 2014. PMCID: PMC4155516
Ramsey LB, Johnson SG, Caudle KE, Haidar CE, Voora D, Wilke RA, Maxwell WD, McLeod HL, Krauss RM, Roden DM, Feng Q, Cooper-DeHoff RM, Gong L, Klein TE, Wadelius M, Niemi M. The Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline for SLCO1B1 and simvastatin-induced myopathy: 2014 update. Clin Pharmacol Ther 96(4):423-428, 2014. Epub 2014 Jun 11. PMCID: PMC4169720
Relling MV, McDonagh EM, Chang T, Caudle KE, McLeod HL, Haidar CE, Klein T, Luzzatto L. Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for Rasburicase Therapy in the Context of G6PD Deficiency Genotype. Clin Pharmacol Ther 96(2):169-174, 2014. Epub 2014 May 2. PMCID: PMC4111801
Hoffman JM, Haidar CE, Wilkinson MR, Crews KR, Baker DK, Kornegay NM, Yang W, Pui C-H, Reiss UM, Gaur AH, Howard SC, Evans WE, Broeckel U, Relling MV. PG4KDS: A model for the clinical implementation of pre-emptive pharmacogenetics. Am J Med Genet C Semin Med Genet 166C(1):45-55, 2014. Epub 2014 May 11. PMCID: PMC4056586
Crews KR, Gaedigk A, Dunnenberger HM, Leeder JS, Klein TE, Caudle KE, Haidar CE, Shen DD, Callaghan JT, Sadhasivam S, Prows CA, Kharasch ED, Skaar TC. Clinical Pharmacogenetics Implementation Consortium guidelines for Cytochrome P450 2D6 genotype and codeine therapy: 2014 update. Clin Pharmacol Ther 95(4):376-382, 2014. Epub 2014 Jan 23. PMCID: PMC3975215
Barbarino JM, Haidar CE, Klein TE, Altman RB. PharmGKB summary: very important pharmacogene information for UGT1A1. Pharmacogenet Genomics 24(3):177-183, 2014. PMCID: PMC4091838
Bell GC, Crews KR, Wilkinson MR, Haidar CE, Hicks JK, Baker DK, Kornegay NM, Yang W, Cross SJ, Howard SC, Freimuth RR, Evans WE, Broeckel U, Relling MV, Hoffman JM. Development and use of active clinical decision support for preemptive pharmacogenomics. J Am Med Inform Assoc 21(e1):e93-99, 2014. Epub 2013 Aug 26. PMCID: PMC3957400
Hicks JK, Crews KR, Hoffman JM, Kornegay NM, Wilkinson MR, Lorier R, Stoddard A, Yang W, Smith C, Fernandez CA, Cross SJ, Haidar C, Baker DK, Howard SC, Evans WE, Broeckel U, Relling MV. A clinician-driven automated system for integration of pharmacogenetic interpretations into an electronic medical record. Clin Pharmacol Ther 92(5):563-566, 2012. Epub 2012 Sep 19. PMCID: PMC3589522
Perko R, Harreld JH, Helton KJ, Sabin ND, Haidar CE, Wright KD. What goes around comes around? Wernicke encephalopathy and the nationwide shortage of intravenous multivitamins revisited. J Clin Oncol 30(31):e318-e320, 2012. Epub 2012 Sep 24. PMCID: PMC3478580.
Haidar C, Jeha S. Drug interactions in childhood cancer. Lancet Oncol 12(1):92-99, 2011. Epub 2010 Sep 22. Review. PMID: 20869315
Finks SW, Oliphant CS, Manguso AH, Rogers KC, Bridges G, Haidar CE, Lee KR, Lee M, Lobo B, May AM, Reaves A, Swanson JM, Swims M, Vinson J, Yates ME. Activities of Memphis-area hospitals to meet National Patient Safety Goals for warfarin therapy. Am J Health Syst Pharm 66(24):2179-2188, 2009. PubMed PMID: 19966086.
Last update: January 2024