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Qian Li, PhD
Qian Li, PhD

Qian Li, PhD

Assistant Member, St. Jude Faculty

Departments

Education

Postdoctoral Fellowship - Moffitt Cancer Center, Tampa, FL
Postdoctoral Fellowship - University of Kansas Medical Center, Kansas City, KS
PhD (Statistics) - University of Missouri, Kansas City, MO
MS (Statistics) - University of Missouri, Kansas City, MO
BS (Mathematics) - Sichuan University, China

Research Interests

  • Statistical and machine learning methods for high-dimensional omics data
  • Integrative analysis in multi-omics studies
  • Longitudinal and time series models

Selected Publications

Meng G, Pan Y, Tang T, Zhang L, Cui Y, Schumacher F, Wang M, Wang R, He S, Krischer J, Li Q*, Feng H*. imply: improving cell-type deconvolution accuracy using personalized reference profiles. Genome Med. 2024 Apr 29;16(1):65. doi: 10.1186/s13073-024-01338-z (*co-corresponding author).

Pan Y, Wang X, Sun J, Liu C, Peng J, Li Q*. Multimodal joint deconvolution and integrative signature selection in proteomics. Commun Biol. 2024 Apr 24;7(1):493. doi: 10.1038/s42003-024-06155-z. (*senior and corresponding author).

Plonski N-M, Pan Y, Chen C, Dong Q, Zhang X, Song N, Shelton K, Easton J, Mulder H, Zhang J, Neale G, Walker E, Wang H, Webster R, Brinkman T, Krull KR, Armstrong GT, Ness KK, Hudson MM, Li Q*, Huang I-C*, Wang Z*. Health-Related quality of life and DNA Methylation-Based aging biomarkers among survivors of childhood cancer. J Natl Cancer Inst. 2024 Mar 5:djae046. doi: 10.1093/jnci/djae046. Epub ahead of print. (*co-senior author).

Feng H*, Meng G, Lin T, Parikh H, Pan Y, Li Z, Krischer J and Li Q*. ISLET: individual-specific reference panel recovery improves cell-type-specific inference. Genome Biol. 2023 Jul 26;24(1):174. doi: 10.1186/s13059-023-03014-8. (*senior and co-corresponding author)

Plonski N-M, Chen C, Dong Q, Qin N, Song N, Shelton K, Finch E, Easton J, Mulder H, Zhang J, Neale G; Walker E, Wang H, Krull K, Ness KK, Hudson MM, Robison LL, Li Q, Williams AL, Wang Z. Epigenetic age in peripheral blood among children, adolescent, and adult survivors of childhood cancer. JAMA Netw Open. 2023 Apr 3;6(4):e2310325. doi: 10.1001/jamanetworkopen.2023.10325.

Stahl M, Li Q, Gragert L, Aronsson C, Lindfors K, Kurppa K, Koletzko S, Ilonen J, Rewers M, Agardh D, Hagopian W, Liu E, and the TEDDY Study Group. Incidence of Pediatric Celiac Disease Varies by Region: Celiac Disease Varies by Region. Am J Gastroenterol. 2023 Mar 1;118(3):539-545. doi: 10.14309/ajg.0000000000002056.

Song N, Dong Q, Chen C, Li Q, Mulder H, Plyler E, Easton J, Walker E, Olson S, Neale G, Krull KR, Srivastava DK, Ness KK, Zhang J, Hudson MM, Robison LL, Huang I-C, Wang Z. Social-epigenetic mediators for racial disparities in pulmonary impairment among childhood cancer survivors. Cancer Commun (Lond). 2023 Feb;43(2):290-293. doi: 10.1002/cac2.12371.

Ahmed KT, Cheng S, Li Q, Yong J, Zhang W. Incomplete time-series gene expression in integrative study for islet autoimmunity prediction. Brief Bioinform. 2023 Jan 19;24(1):bbac537. doi: 10.1093/bib/bbac537.

Dong Q, Song N, Qin N, Chen C, Li Z, Sun X, Easton J, Mulder H, Plyler E, Neale G, Walker E, Li Q, Ma X, Chen X, Huang IC, Yasui Y, Ness KK, Zhang J, Hudson MM, Robison LL, Wang Z. Genome-wide association studies identify novel genetic loci for epigenetic age acceleration among survivors of childhood cancer. Genome Med. 2022 Mar 22;14(1):32. doi: 10.1186/s13073-022-01038-6.

Li Q*, Liu X, Yang J, Lernmark A, Hagopian W, Rewers M, She J-X, Toppari J, Ziegler AG, Akolkar B, Krischer JP, and the TEDDY Study Group. Plasma metabolome and circulating vitamins stratified onset age of an initial islet autoantibody and progression to type 1 diabetes: the TEDDY study. Diabetes. 2021 Jan;70(1):282-292. doi: 10.2337/db20-0696. (*corresponding author).

Li Q*. Location Multiplicative Error Models With Quasi Maximum Likelihood Estimation. J Time Series Anal. 2020 May;41(3):365-486. doi:10.1111/jtsa.12513. (*corresponding author).

Li Q*, Parikh H, Butterworth MD, Lernmark A, Hagopian W, Rewers M, She J-X, Toppar J, Ziegler AG, Akolkar B, Fiehn O, Fan S, Krischer JP*, and the TEDDY Study Group. Longitudinal metabolome-wide signals prior to the appearance of a first islet autoantibody in children participating in the TEDDY study. Diabetes. 2020 Mar;69(3):465-476. doi: 10.2337/db19-0756. (*co-corresponding authors).

Li Q, Fisher K, Meng W, Welsh E, Fang B, Haura E, Koomen J, Eschrich S, Fridley BL, Chen YA. GMSimpute: a generalized two-step Lasso approach to impute missing values in label-free mass spectrum analysis. Bioinformatics. 2020 Jan 1;36(1):257-263. doi: 10.1093/bioinformatics/btz488.

Last update: June 2024

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