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Melissa M. Hudson, MD
Melissa M. Hudson, MD

Melissa M. Hudson, MD

Member, St. Jude Faculty

  • Director, Cancer Survivorship Division
  • Associate Director, Population Sciences
  • The Charles E. Williams Endowed Chair of Oncology-Cancer Survivorship

Departments

Divisions

Education

BS – Texas A & M University, College Station, Texas (1979)
MD – University of Texas Medical School at Houston (1983)

Research Interests

  • Disease burden after childhood cancer
  • Health status and quality of life after childhood cancer
  • Pediatric cancer survivorship care guideline development

Selected Publications

Full list of publications

Williams AM, Mandelblatt J, Wang M, Armstrong GT, Bhakta N, Brinkman TM, Chemaitilly W, Ehrhardt MJ, Mulrooney DA, Small BJ, Wang Z, Srivastava D, Robison LL, Hudson MM, Ness KK, Krull KR. Premature aging as an accumulation of deficits in young adult survivors of pediatric cancer. J Natl Cancer Inst 2022 Nov 12 (Epub).

Sapkota Y, Qiu W, Dixon SB, Wilson CL, Wang Z, Zhang J, Leisenring W, Chow EJ, Bhatia S, Armstrong GT, Robison LL, Hudson MM, Delaney A, Yasui Y. Genetic risk score enhances the risk prediction of severe obesity in adult survivors of childhood cancer. Nat Med 28(8):1590-98, 2022. 

Sapkota Y, Ehrhardt MJ, Qin N, Wang Z, Liu Q, Qiu W, Shelton K, Shao Y, Plyler E, Mulder HL, Easton J, Michael JR, Burridge PW, Wang X, Wilson CL, Jefferies JL, Chow EJ, Oeffinger KC, Morton LM, Li C, Yang JJ, Zhang J, Bhatia S, Mulrooney DA, Hudson MM, Robison LL, Armstrong GT, Yasui Y. A novel locus on 6p21.2 for cancer treatment-induced cardiac dysfunction among childhood cancer survivors. J Natl Cancer Inst 114(8):1109-16, 2022. 

Williams AM, Krull KR, Howell CR, Banerjee P, Brinkman TM, Kaste SC, Partin RE, Srivastava D, Yasui Y, Armstrong GT, Robison LL, Hudson MM, Ness KK. Physiologic frailty and neurocognitive decline among young-adult childhood cancer survivors: A prospective study from the St. Jude Lifetime Cohort. J Clin Oncol Nov 1;39(31):3485-95, 2021.

Ehrhardt MJ, Flerlage JE, Armenian SH, Castellino SM, Hodgson DC, Hudson MM. Integration of pediatric Hodgkin lymphoma treatment and late effects guidelines: seeing the forest beyond the trees. J Natl Compr Canc Netw 19(6):755-64, 2021. Role: Senior author

Metzger ML, Link MP, Billett AL, Flerlage J, Lucas JT Jr, Mandrell BN, Ehrhardt MJ, Bhakta N, Yock TI, Friedmann AM, de Alarcon P, Luna-Fineman S, Larsen E, Kaste SC, Shulkin B, Lu Z, Li C, Hiniker SM, Donaldson SS, Hudson MM, Krasin MJ. Excellent outcome for pediatric patients with high-risk Hodgkin lymphoma treated with brentuximab vedotin and risk-adapted residual node radiation. J Clin Oncol 39(20):2276-83, 2021.

Delaney A, Howell CR, Krull KR, Brinkman TM, Armstrong GT, Chemaitilly W, Wilson CL, Mulrooney DA, Wang Z, Lanctot JQ, Johnson RE, Krull MR, Partin RE, Shelton KC, Srivastava DK, Robison LL, Hudson MM, Ness KK. Progression of frailty in survivors of childhood cancer: a St. Jude Lifetime Cohort Report. J Natl Cancer Inst Oct 1;113(10):1415-21, 2021.

Ehrhardt MJ, Ward ZJ, Liu Q, Chaudhry A, Nohria A, Border W, Fulbright JM, Mulrooney DA, Oeffinger KC, Nathan PC, Leisenring WM, Constine LS, Gibson TM, Chow EJ, Howell RM, Robison LL, Armstrong GT, Hudson MM, Diller L, Yasui Y, Armenian SH, Yeh JM. Cost-effectiveness of the International Late Effects of Childhood Cancer Guideline Harmonization Group Screening Guidelines to prevent heart failure in survivors of childhood cancer. J Clin Oncol 38(33):3851-62, 2020.

Dixon SB, Chen Y, Yasui Y, Pui CH, Hunger SP, Silverman LB, Ness KK, Green DM, Howell RM, Leisenring WM, Kadan-Lottick NS, Krull KR, Oeffinger KC, Neglia JP, Mertens AC, Hudson MM, Robison LL, Armstrong GT, Nathan PC. Reduced morbidity and mortality in survivors of childhood acute lymphoblastic leukemia: a report from the Childhood Cancer Survivor Study. J Clin Oncol Oct 10;38(29):3418-29, 2020.

Hayek S, Gibson TM, Leisenring WM, Guida JL, Gramatges MM, Lupo PJ, Howell RM, Oeffinger KC, Bhatia S, Edelstein K, Hudson MM, Robison LL, Nathan PC, Yasui Y, Krull KR, Armstrong GT, Ness KK. Prevalence and predictors of frailty in childhood cancer survivors and siblings: a report from the Childhood Cancer Survivor Study.  J Clin Oncol 38(3):232-47, 2020.

Wilson CL, Brinkman TM, Cook C, Huang S, Hyun G, Green DM, Furman WL, Bhakta N, Ehrhardt MJ, Krasin MJ, Robison LL, Ness KK, Hudson MM. Clinically ascertained health outcomes, quality of life, and social attainment among adult survivors of neuroblastoma: A report from the St. Jude Lifetime Cohort. Cancer 126(6):1330-8, 2020. Role: Senior author

Mulrooney DA, Hyun G, Ness KK, Ehrhardt MJ, Yasui Y, Duprez D, Howell RM, Leisenring WM, Constine LS, Tonorezos E, Gibson TM, Robison LL, Oeffinger KC, Hudson MM, Armstrong GT. Major cardiac events for adult survivors of childhood cancer diagnosed between 1970 and 1999: report from the Childhood Cancer Survivor Study cohort. BMJ 368:l6794, 2020.

Song N, Li Z, Qin N, Howell CR, Wilson CL, Easton J, Mulder HL, Edmonson MN, Rusch M, Zhang J, Hudson MM, Yasui Y, Robison LL, Ness KK, Wang Z. Shortened leukocyte telomere length associates with an increased prevalence of chronic health conditions among survivors of childhood cancer: a report from the St. Jude Lifetime Cohort. Clin Cancer Res May 15;26(10):2362-71, 2020. 

Ness KK, Plana JC, Joshi VM, Luepker RV, Durand JB, Green DM, Partin RE, Santucci AK, Howell RM, Srivastava DK, Hudson MM, Robison LL, Armstrong GT. Exercise intolerance, mortality, and organ system impairment in adult survivors of childhood cancer. J Clin Oncol 38(1):29-42, 2019.

Chemaitilly W, Liu Q, van Iersel L, Ness KK, Li Z, Wilson CL, Brinkman TM, Klosky JL, Barnes N, Clark KL, Howell RM, Smith SA, Krasin MJ, Metzger ML, Armstrong GT, Bishop MW, van Santen HM, Pui CH, Srivastava DK, Yasui Y, Hudson MM, Robison LL, Green DM, Sklar CA. Leydig cell function in male survivors of childhood cancer: a report from the St. Jude Lifetime Cohort Study. J Clin Oncol 37(32):3018-31, 2019.

Wang Z, Wilson CL, Armstrong GT, Hudson MM, Zhang J, Nichols KE, Robison LL. Association of germline BRCA2 mutations with the risk of pediatric or adolescent non-Hodgkin lymphoma. JAMA Oncol Sep 1;5(9):1362-4, 2019. 

van Atteveld JE, Pluijm SMF, Ness KK, Hudson MM, Chemaitilly W, Kaste SC, Robison LL, Neggers SJCMM, Yasui Y, van den Heuvel-Eibrink MM, Wilson CL. Prediction of low and very low bone mineral density among adult survivors of childhood cancer. J Clin Oncol 37(25):2217-25, 2019.

Banerjee P, Rossi MG, Anghelescu DL, Liu W, Breazeale AM, Reddick WE, Glass JO, Phillips NS, Jacola LM, Sabin ND, Inaba H, Srivastava D, Robison LL, Pui CH, Hudson MM, Krull KR. Association between anesthesia exposure and neurocognitive and neuroimaging outcomes in long-term survivors of childhood acute lymphoblastic leukemia. JAMA Oncol Oct 1;5(10):1456-63, 2019.

Ehrhardt MJ, Chen Y, Sandlund JT, Bluhm EC, Hayashi RJ, Becktell K, Leisenring WM, Metzger ML, Ness KK, Krull KR, Oeffinger KC, Gibson TM, Cairo MS, Gross TG, Robison LL, Armstrong GT, Yasui Y, Hudson MM, Mulrooney DA. Late health outcomes after contemporary Lymphome Malin De Burkitt Therapy for mature B-cell non-Hodgkin lymphoma: a report from the Childhood Cancer Survivor Study. J Clin Oncol 37(28):2556-70, 2019.

Mulrooney DA, Hyun G, Ness KK, Bhakta N, Pui CH, Ehrhardt MJ, Krull KR, Crom DB, Chemaitilly W, Srivastava DK, Relling MV, Jeha S, Green DM, Yasui Y, Robison LL, Hudson MM. The changing burden of long-term health outcomes in survivors of childhood acute lymphoblastic leukaemia: a retrospective analysis of the St. Jude Lifetime Cohort Study. Lancet Haematol 6(6):e306-16, 2019. Role: Senior author

Ehrhardt MJ, Howell CR, Hale K, Baassiri MJ, Rodriguez C, Wilson CL, Joshi SS, Lemond TC, Shope S, Howell RM, Wang Z, Srivastava D, Mulrooney DA, Zhang J, Robison LL, Ness KK, Hudson MM. Subsequent breast cancer in female childhood cancer survivors in the St. Jude Lifetime Cohort Study (SJLIFE). J Clin Oncol 37(19):1647-56, 2019. Role: Senior author

Clemens E, van den Heuvel – Eibrink MM, Mulder RL, Kremer LCM, Hudson MM, Skinner R, Constine LS, Bass JK, Kuehni CE, Langer T, van Dalen EC, Bardi E, Bonne NX, Brock PR, Brooks B, Carleton B, Caron E, Chang KW, Johnston K, Knight K, Nathan PC, Orgel E, Prasad PK, Rottenberg J, Scheinemann K, de Vries ACH, Walwyn T, Weiss A, Am Zehnhoff – Dinnesen A, Cohn RJ, Landier W; International Guideline Harmonization Group ototoxicity group. Recommendations for ototoxicity surveillance for childhood, adolescent, and young adult cancer survivors: a report from the International Late Effects of Childhood Cancer Guideline Harmonization Group in collaboration with the PanCare Consortium. Lancet Oncol 20(1):e29-41, 2019.

Feijen EAM, Leisenring WM, Stratton KL, Ness KK, van der Pal HJH, van Dalen EC, Armstrong GT, Aune GJ, Green DM, Hudson MM, Loonen J, Oeffinger KC, Robison LL, Yasui Y, Kremer LCM, Chow EJ. Derivation of anthracycline and anthraquinone equivalence ratios to doxorubicin for late – onset cardiotoxicity. JAMA Oncol 5(6):864-71, 2019.

Huang IC, Bhakta N, Brinkman TM, Klosky JL, Krull KR, Srivastava D, Hudson MM, Robison LL. Determinants and consequences of financial hardship among adult survivors of childhood cancer: a report from the St. Jude Lifetime Cohort Study. J Natl Cancer Inst 111(2):189–200, 2019.

Gibson TM, Mostoufi – Moab S, Stratton KL, Leisenring WM, Barnea D, Chow EJ, Donaldson SS, Howell RM, Hudson MM, Mahajan A, Nathan PC, Ness KK, Sklar CA, Tonorezos ES, Weldon CB, Wells EM, Yasui Y, Armstrong GT, Robison LL, Oeffinger KC. Temporal patterns in the risk of chronic health conditions in survivors of childhood cancer diagnosed 1970 – 99: a report from the Childhood Cancer Survivor Study cohort. Lancet Oncol 19(12):1590-601, 2018.

Brinkman TM, Ness KK, Li Z, Huang IC, Krull KR, Gajjar A, Merchant TE, Klosky JL, Partin RE, Olsson IT, Boop F, Klimo P Jr, Chemaitilly W, Khan RB, Srivastava D, Robison LL, Hudson MM, Armstrong GT. Attainment of functional and social independence in adult survivors of pediatric CNS tumors: a report from the St. Jude Lifetime Cohort Study. J Clin Oncol 36(27):2762-69, 2018.

Wang Z, Wilson CL, Easton J, Thrasher A, Mulder H, Liu Q, Hedges DJ, Wang S, Rusch MC, Edmonson MN, Levy S, Lanctot JQ, Caron E, Shelton K, Currie K, Lear M, Patel A, Rosencrance C, Shao Y, Vadodaria B, Yergeau D, Sapkota Y, Brooke RJ, Moon W, Rampersaud E, Ma X, Chang TC, Rice SV, Pepper C, Zhou X, Chen X, Chen W, Jones A, Boone B, Ehrhardt MJ, Krasin MJ, Howell RM, Phillips NS, Lewis C, Srivastava D, Pui CH, Kesserwan CA, Wu G, Nichols KE, Downing JR, Hudson MM, Yasui Y, Robison LL, Zhang J. Genetic risk for subsequent neoplasms among long – term survivors of childhood cancer. J Clin Oncol 36(20):2078-87, 2018.

Last update: November 2022

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