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ZIC1 gene drives distinct medulloblastoma types in different ways
01/08/2025
Discover research showing how the context of distinct & opposing mutations in the ZIC1 gene drive Group 4 (G4) and sonic hedgehog (SHH) medulloblastoma types.
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St. Jude scientists create scalable solution for analyzing single-cell data
01/08/2025
Explore how Consensus and Scalable Inference of Gene Expression Programs (CSI-GEP)’s unsupervised machine learning provides unbiased single-cell RNA analysis.
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Signaling circuit interplay pushes newborn neurons out of the neuronal nest
01/07/2025
See how Netrin-1, Siah2, Pard3 and JamC interconnect in a coincidence detection circuit in neuronal development and migration from germinal zone
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Discovery of ‘pliancy genes’ showcases role of latent epigenetic programs in retinal recovery
01/02/2025
Learn how the discovery of pliancy genes by scientists at St. Jude showcases the role of latent epigenetic programs in the retina’s response to stress.
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Mitochondrial DNA plays an underappreciated role in leukemia development
01/01/2025
See how mitochondrial DNA (mtDNA) mutation affects leukemogenesis by altering metabolic pathways via pyruvate dehydrogenase and affecting cell plasticity
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Brain map clarifies neuronal connectivity behind motor function
12/23/2024
See how St. Jude researchers tracked spinal cord V1 interneuron connections with neurons in the brain to see how they work in motor function signaling
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Universal barcodes unlock fast-paced small molecule synthesis
12/11/2024
Learn how St. Jude scientists discovered a universal barcode in fragmentation patterns to revolutionize chemical reaction analysis and small molecule synthesis.
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Research links a genetic risk for schizophrenia to a malformed skull
12/05/2024
See how St. Jude scientists study 22q schizophrenia disorder finding flocculus and paraflocculus growth in cerebellum curbed by lack of skull growth gene Tbx1
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Predicting cardiac issues in cancer survivors using a serum protein panel test
12/03/2024
See how a blood serum panel of 27 proteins can accurately predict anthracycline-related cardiomyopathy risk in subclinical pediatric cancer survivors
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St. Jude appoints leading scientist to create groundbreaking Center of Excellence for Structural Cell Biology
11/21/2024
Georgios Skiniotis, PhD, to develop and lead new center focusing on advanced imaging techniques, including cryo-ET.
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