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ATRT molecular groups: looking at the biology from the clinic
Scientists at St. Jude Children’s Research Hospital are learning more about what the molecular groups of a rare pediatric brain tumor mean for clinical care.
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Martine Roussel, Ph.D., elected to the AACR Academy Class of 2021
Martine Roussel, Ph.D., has been elected to the 2021 Class of Fellows of the American Association for Cancer Research.
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Excellent outcomes reported for first targeted frontline therapy for high-risk pediatric Hodgkin lymphoma
Results from a collaborative multi-site clinical trial show the success of adding brentuximab vedotin, reducing radiation.
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By age 10, retinoblastoma patients’ learning and life skills rebound
St. Jude researchers found that retinoblastoma survivors functioned within the normal range of learning and life skills after five years.
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Socioeconomic status plays a major role in cognitive outcomes
St. Jude scientists are studying the risk factors associated with cancer treatments and its effects on cognition.
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Signals from muscle protect from dementia
Scientists at St. Jude are studying how signals sent from skeletal muscle affect the brain.
Advanced Research Center Highlights
Mosaic microscope moves to new facility
As investigators began to move their labs to the new Advanced Research Center this summer, some equipment — such as the 1,400 lb. Mosaic microscope — required special handling. This delicate and highly sophisticated tool allows scientists to image deeper into tissues than has been possible before. A next-generation adaptive optics microscope, it is one of only a handful in development. Situated in its new home in the Advanced Research Center, it will help scientists answer biological questions that other systems cannot address.
Taking science to new heights
The sheer scale of the St. Jude Advanced Research Center hints at the power of science to transform the human condition.
During the summer of 2021, scientists in the fields of developmental neurobiology, immunology, cell and molecular biology, gene editing, metabolomics, advanced microscopy, epigenetics and genomics began to move into the facility.
Designed to foster collaboration and innovation, the building contains nearly 1.8 million square feet of sheetrock, the city’s tallest glass window, and enough rebar to stretch from Memphis to Montreal. In spite of its floor-to-ceiling windows and state-of-the-art technology, the power of this building resides in the hearts and minds of the scientists who work there. In the coming years, work conducted within these walls will accelerate progress globally.
From Promise, Summer 2021
More articles from this issue
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Something to Dance About: A Gentler Approach to Transplants
Using a gentler chemotherapy and radiation conditioning regimen, the Sickle Cell Disease Hematopoietic Cell Transplantation (SCDHCT) study aims to cure children with severe sickle cell disease and reduce side effects and subsequent health issues.
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The 2022–27 St. Jude Strategic Plan: Accelerating Progress Globally
Learn how St. Jude can uniquely accelerate progress to advance cures, and means of prevention, for pediatric catastrophic diseases through fundamental science, global impact, and workforce and environment.
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von Hippel-Lindau: Focusing on an Invisible Foe
As a von Hippel-Lindau Clinical Care Center, St. Jude can focus the treatment experience for families affected by the rare genetic disorder.
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Sharing High-tech Tools with the World
Scientists at St. Jude work behind the scenes – finding faster and better ways to sift through DNA data and save the lives of children around the world.
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Shining a Light on Mucositis
Light therapy, or photobiomodulation therapy, is a painless and potential solution to reduce oral mucositis in children and adolescents who have had bone marrow transplantation.
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A Global View of ALL
St. Jude takes steps to improve the outlook for children with acute lymphoblastic leukemia in China and around the world.
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Treatment Refinements Offer Global Benefits
Results from clinical trials in Recife, Brazil, and Cairo, Egypt, offer hope to children in low- and middle-income countries worldwide.
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Life after St. Jude: ‘Cured’ Is Only the Beginning
Childhood cancer survivor Katie Chinn Weyer learns to navigate life —and her health — after treatment.