St. Jude structural biologist Eric Enemark, PhD, and others recently captured an atomic-scale image of the structure of DNA replication machinery. Enemark began to ponder that structure. He thought it might help solve a mystery at the heart of cell division. Using scrap lumber, he built a simple model. This low-tech machine shows how double-stranded DNA could begin separating to single-stranded DNA, which can be copied in advance of cell division. Nature Communications published a report on his research.
From Promise, Autumn 2019
More articles from this issue
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St. Jude LIFE Celebrates Milestone
St. Jude welcomes its 5,000th patient back to campus in an extraordinary study designed to help the survivors of today and the children of tomorrow.
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Blue-Sky Projects Accelerate Progress
St. Jude identifies and pursues bold new projects that could transform science and medicine.
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Where Leukemia Hides, the Immune System Seeks
Research challenges the notion that cancer cells must contain multiple mutations to prompt an immune response.
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It's a BRAVE New World for Mobility
The new BRAVE (Beginning Restorative Activities Very Early) program seeks to help mobilized patients as soon as possible to decrease their time in the pediatric intensive care unit and reduce delirium and ventilation time.
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Together: Powered by St. Jude
A new website brings families and St. Jude experts together to face pediatric cancer. This online resource offers trustworthy resources for families around the world to learn about childhood cancer.
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Global Child Health: Spreading Knowledge, Saving Children
A unique Master of Science in Global Child Health trains health care professionals around the world. This program incorporates the world-renowned faculty of the St. Jude Children’s Research Hospital Graduate School of Biomedical Sciences with the expertise of faculty in Global Pediatric Medicine.
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Half-Matched Transplants, Whole Hope for Cures
A new study for half-matched transplants aims to cure high-risk blood cancers. The HAP2HCT clinical trial aims to kill remaining cancer cells, reduce the risk of GVHD and help patients’ immune systems recover quickly.
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Organizing Organelles
How do cells organize proteins without membranes? St. Jude scientists unlock the mysteries of liquid-liquid phase separation, or LLPS, to better understand membraneless organelles.
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Life after St. Jude: Hoop Dreams
Learn about the global cancer burden in low- and middle-income countries, what we can learn from rare disorders, new findings about the BRACA2 gene, and other recent scientific discoveries.
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Super-conducting Magnet
St. Jude takes delivery of the world’s largest superconducting magnet.
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News and Highlights - Autumn 2019
Learn about the global cancer burden in low- and middle-income countries, what we can learn from rare disorders, new findings about the BRACA2 gene, and other recent scientific discoveries.