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Finding Cures. Saving Children.
Epidemiology and Cancer Control
The Department of Epidemiology and Cancer Control, established in November 2005, is building an internationally recognized program for the conduct of etiology (causes and origins of disease), outcomes, and interventional research in childhood cancer and hematologic conditions.
The department was established as part of an aggressive expansion of the Cancer Prevention and Control Research Program within the St. Jude Cancer Center. The department has significantly increased St. Jude’s ability to include preventive medicine in its overall goal to reduce morbidity and mortality from childhood cancer.
Leslie L. Robison, PhD, chair of the department, is principal investigator of the Childhood Cancer Survivorship Study (CCSS), now anchored at St. Jude. This multi-institutional consortium markedly expands the scope of survivorship research and complement the work of the After Completion of Therapy (ACT) clinic. CCSS provides the availability of a cohort of approximately 28,000 five-year survivors of pediatric cancer.
The Department of Epidemiology and Cancer Control includes three focused areas of research.
Etiology Research
The emphasis of the Etiology Research program is molecular etiology with investigations focusing on genetic and/or environmental factors in laboratory- and non-laboratory-based research developed through a partnership with the International Outreach Program. The program will also expand secondary malignancies research.
Outcomes Research
The foundation of the Outcomes Research program consists of two remarkable resources; the St. Jude’s After Completion of Therapy clinic and the Childhood Cancer Survivor Study. In combination, these two resources represent an unparalleled opportunity to conduct innovative clinical and analytic research into the mechanisms of and risk factors for adverse late events.
Interventional Research
The Interventional Research program will develop interventional protocols in supportive care and behavioral interventions. The proposed St. Jude Consortium for Interventional Research, which will consist of several centers committed to enroll patients on cancer control protocols developed by St. Jude, will be its foundation.
Leslie L. Robison, PhD, chairs the Department of Epidemiology and Cancer Control.
